Hematological and biochemical studies of fluorine poisoning in chickens, a trial for treatment

Seddek, Abdel Latif Sh.; Abdel-Hamid, Ahlam; Ibrahim, Thabet A.; El-Nasser, Mahmoud Abd

doi:10.1016/s0378-4274(96)80385-7

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“…The egg production rate over 70 days showed a tendency to decrease as the level of added fluoride rose. When broilers and laying hens were fed sodium fluoride at a level of 1000 and 1500 mg/kg feed, respectively, for 3 months, mean egg weight, feed consumption and body weight gain decreased (Seddek et al, 1977). Feeding studies with turkeys indicated that levels up to 400 mg F -/kg feed are tolerated over the entire lifespan, whereas feed consumption was decreased when fluorine was present in a concentration of 800 mg/kg feed (Anderson et al, 1955).…”

Section: Poultrymentioning

confidence: 99%

Opinion of the Scientific Panel on contaminants in the food chain [CONTAM] related to Fluorine as undesirable substance in animal feed

2004

EFSA Journal

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Section: Poultrymentioning

confidence: 99%

Opinion of the Scientific Panel on contaminants in the food chain [CONTAM] related to Fluorine as undesirable substance in animal feed

2004

EFSA Journal

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In Vitro Effect of Sodium Fluoride on Malondialdehyde Concentration and on Superoxide Dismutase, Catalase, and Glutathione Peroxidase in Human Erythrocytes

Gutiérrez‐Salinas

García-Ortiz

Morales-González

et al. 2013

The Scientific World Journal

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The aim of this paper was to describe the in vitro effect of sodium fluoride (NaF) on the specific activity of the major erythrocyte antioxidant enzymes, as well as on the membrane malondialdehyde concentration, as indicators of oxidative stress. For this purpose, human erythrocytes were incubated with NaF (0, 7, 28, 56, and 100 μg/mL) or NaF (100 μg/mL) + vitamin E (1, 2.5, 5 and 10 μg/mL). The malondialdehyde (MDA) concentration on the surface of the erythrocytes was determined, as were the enzymatic activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GlPx). Our results demonstrated that erythrocytes incubated with increasing NaF concentrations had an increased MDA concentration, along with decreased activity of antioxidant enzymes. The presence of vitamin E partially reversed the toxic effects of NaF on erythrocytes. These findings suggest that NaF induces oxidative stress in erythrocytes in vitro, and this stress is partially reversed by the presence of vitamin E.

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Hematological and biochemical studies of fluorine poisoning in chickens, a trial for treatment

Cited by 2 publications

References 0 publications

Opinion of the Scientific Panel on contaminants in the food chain [CONTAM] related to Fluorine as undesirable substance in animal feed

Opinion of the Scientific Panel on contaminants in the food chain [CONTAM] related to Fluorine as undesirable substance in animal feed

In Vitro Effect of Sodium Fluoride on Malondialdehyde Concentration and on Superoxide Dismutase, Catalase, and Glutathione Peroxidase in Human Erythrocytes

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