Hematological changes in Covid-19 infections

Duarte, Fernando Barroso; Lemes, Romélia Pinheiro Gonçalves; Duarte, Isabella Araújo; Duarte, Beatrice Araújo; Duarte, J.

doi:10.1590/1806-9282.66.2.99

Cited by 12 publications

(12 citation statements)

References 3 publications

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“…There is currently insufficient understanding accessible, and breakthroughs in diagnostic technologies and treatment are urgently needed. Diagnostic procedures, such as RT-PCR and antibody testing, are critical for epidemiology and early illness diagnosis [30]. Clinical, hematological, and biochemical markers must be monitored as part of COVID-19 patient treatment.…”

Section: Discussionmentioning

confidence: 99%

Biochemical Manifestations of Sars-CoV-2 in Elderly Population (55 Years +): A Retrospective Cohort Study

Manu¹

2022

JCCM

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Background: Several studies have demonstrated that age, comorbidities, and abnormalities in different clinical biomarkers can be important in understanding disease severity. Although clinical features of COVID-19 have been widely described, the assessment of alterations of the most common biochemical markers that are reported in patients with COVID-19 still has not been well established especially in the elderly population.Methods: Here, we report the blood biochemical indicators of fifty-eight elderly patients (Age: 61.03±7.29) with COVID-19. Throatswab upper respiratory samples were obtained from patients, and real-time PCR was used to confirm SARS-CoV-2 infection. Then, biochemical parameters were categorized and analyzed according to these clinical characteristics. This retrospective study involved investigating the medical e-records of COVID-19 positive patients who presented to a COVID-19 centre in Qatar in July 2020.Results: Of the 58 investigated patients, 58.62% were male and 41.38% were Female. 5.17% of the patients had low viral load (i.e., cycle threshold (Ct) ≥ 30) and 94.83% had a high viral load (ie; Ct < 30). Hypocalcemia and uremia affected 12.07% and hypochloremia affected 17.23% of the patients. 27.59% suffered from hyponatremia, 27.59 % had low creatinine, 24.14% had high levels of Alanine transaminase (ALT), 25.86% had high levels of aspartate transferase (AST), and 65.52% had a high level of C-reactive protein (CRP). Conclusion:Elderly COVID-19 positive patients have been shown to have a disturbance in their biochemical parameters. Indeed, various biochemical parameters measured at baseline can provide useful prognostic information among COVID-19-affected patients. It can also help in the early identification of patients who merit aggressive institutional care, thereby potentially mitigating mortality.

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Section: Discussionmentioning

confidence: 99%

Biochemical Manifestations of Sars-CoV-2 in Elderly Population (55 Years +): A Retrospective Cohort Study

Manu¹

2022

JCCM

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“…In emergency settings, during hospitalizations and in the outpatient setting, a hemogram is one of the most affordable and accessible minimally invasive investigations that can be very useful in the management of diseases 6 , 7 . Hemogram-derived ratios (HDR), including neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), monocyte-lymphocyte ratio (MLR), neutrophil-platelet ratio (NPR) and systemic immune-inflammation index (SII), may serve as surrogate markers for systemic inflammation and various studies have shown that they could be very useful and reliable inflammatory markers and predictors of the severity and mortality of COVID-19 8 , 9 , 10 , 11 , 12 .…”

Section: Introductionmentioning

confidence: 99%

Hemograms and serial hemogram-derived ratios in survivors and non-survivors of COVID-19 in Campinas, Brazil

Alagbe

Pedroso

Oliveira

et al. 2024

Hematology, Transfusion and Cell Therapy

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“…In addition of this a number of other body infections are also associated with the infection of COVID-19 virus, which includes, diffuse alveolar damage, acute kidney injury, acute respiratory failure, multiple organ failure, irregular cardiac functions, irregular pattern in the level of oxygen (Zaim et al, 2020). Hematological alterations like White blood cells WBC and Platelets PLT are also detected in the blood samples of corona patients (Duarte et al, 2020). The emergent of new symptoms in different patients and their dynamic changes have led to the development of many biochemical indicators in the laboratory that helps to reflect on the important pathophysiology of the COVID-19 like heart enzymes , liver functions, completed blood counts, kidney functions, Creactive protein CRP, D-dimer and blood gases (Leulseged et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

An overview of COVID 19 effects On Some human Body Function Bio Markers

Al‐Farga

Alkaraan

Afifi

et al. 2022

JCNB

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Despite the emergence of COVID 19 since 20019 and despite the many studies that researchers have raced to uncover the truth about this virus, there is still great ambiguity in everything related to this virus, especially its behavior inside the human body and the body’s reaction to it. The body reaction to COVID 19 differ greatly from one individual to anther in terms of its type and severity. Hence the importance of this review, as if we understand the changes that this virus causes in the human body and are able to measure its bioindicators, this gives us the ability to understand the behavior of this virus inside the body and thus enables us to overcome it. The investigation of different biomarkers induced by COVID 19 infection will open the dour to the researchers to understand the molecular mechanism of viral infection gives new diagnostic tools for the viral infection and gives the researcher a chance for discovering new strategies for COVID 19 treatment and prevention, and invention of new pharmatheutical products for viral treatment.

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Hematological changes in Covid-19 infections

Cited by 12 publications

References 3 publications

Biochemical Manifestations of Sars-CoV-2 in Elderly Population (55 Years +): A Retrospective Cohort Study

Biochemical Manifestations of Sars-CoV-2 in Elderly Population (55 Years +): A Retrospective Cohort Study

Hemograms and serial hemogram-derived ratios in survivors and non-survivors of COVID-19 in Campinas, Brazil

An overview of COVID 19 effects On Some human Body Function Bio Markers

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