Hematology on Twitter

Styczyński, Tomasz; Sadlok, Jagoda; Styczyński, Jan

doi:10.5603/ahp.a2023.0002

Cited by 5 publications

(4 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most common cancer in children is acute lymphoblastic leukemia (ALL), with the highest incidence rate found in the age range of 2-5 years (6.2/100,000 children/ /year). The number of new cases decreases with age from 2.7/100,000/year at age 5-9 to 1.6/100,000/year at age 10-14 [1]. According to the recommendations of the Polish Pediatric Group for the Treatment of Leukemia and Lymphoma, until March 2018 the management of acute lymphoblastic leukemia in children in Poland was carried out according to the ALL International Cooperative Magdalena Cienkusz, Katarzyna Drabko, Vincristine-induced peripheral neuropathy in ALL caregivers or from patients over 16 years of age, and achieving 15 points on the Glasgow Coma Score in the control points.…”

Section: Introductionmentioning

confidence: 92%

The incidence and clinical spectrum of vincristine- induced peripheral neuropathy in patients with acute lymphoblastic leukemia- a prospective study of twenty-nine cases

Cienkusz,

Drabko

2024

Acta Haematol Pol.

View full text Add to dashboard Cite

Introduction: Vincristine is used in many therapeutic schemes of oncological treatment in children, and one of its common complications is neurotoxicity. The aim of this study was to assess the incidence of vincristine-induced polyneuropathy in children treated for acute lymphoblastic leukemia. Secondly, we evaluated the clinical spectrum of chemotherapy-induced peripheral neuropathy. Material and methods:The study included 29 patients with newly diagnosed acute lymphoblastic leukemia who were treated according to the ALL IC-BFM 2009 therapeutic program. The study was designed for the induction remission phase, in which patients received unified anticancer treatment. A neurological assessment was performed on days 1, 8, 15, 22, 29 and 36 of treatment, and consisted of an original questionnaire completed by patients or their caregivers, a physical examination, and a neurological examination. Abnormalities were assessed according to the Common Terminology Criteria for Adverse Events, version 5.0 scale.Results: Symptoms of polyneuropathy occurred in 25 patients (86.2%). Motor neuropathy was the most common type of polyneuropathy in the examined group. In half of the cases, the polyneuropathy was severe, rated at 3 or 4 points. The most serious course manifested itself in three patients in severe gastrointestinal ileus with subsequent intestinal perforation. In another case, rated at 4 points, breathing disorders occurred with apnea episodes.Conclusions: Vincristine-induced polyneuropathy is common in children with acute lymphoblastic leukemia in the induction of remission phase, and is severe in half of cases. In the pediatric population, in contrast to adults, vincristine--induced polyneuropathy motor symptoms are predominant.

show abstract

Section: Introductionmentioning

confidence: 92%

The incidence and clinical spectrum of vincristine- induced peripheral neuropathy in patients with acute lymphoblastic leukemia- a prospective study of twenty-nine cases

Cienkusz,

Drabko

2024

Acta Haematol Pol.

View full text Add to dashboard Cite

show abstract

“…3. CAR-T cell structure and evolution CAR comprises three major components: an extracellular domain, a transmembrane domain, and an intracellular domain [4,5]. The extracellular domain comprises a signal peptide, a tumor-associated antigen (TAA) recognition region, and a spacer.…”

Section: Origin Of Car-t Cellsmentioning

confidence: 99%

CAR-T Cells

Huang

2024

View full text Add to dashboard Cite

show abstract

“…While less proliferative than the field of oncology, hematology has a growing presence on Twitter [ 73 ]. With less of a focus on patient engagement, hematology-related content is dominated by academic societies and individual providers/researchers [ 74 ]. While some providers share personal anecdotes or opinions on “hot topics,” the majority of content is focused on hematology.…”

Section: Reviewmentioning

confidence: 99%

A Scoping Review of Physician Advocacy on Twitter

Cahill¹,

Carlson²

2023

Cureus

View full text Add to dashboard Cite

Twitter has been adopted by physicians across most medical specialties; it allows for the wide dissemination of information and calls to action, brings new stakeholders into collations, promotes academic engagement, and fosters collaboration between academia and private practice. In this review of the literature, we briefly outline the state of advocacy in health care and summarize current Twitter-based advocacy efforts in the major specialties of health care, identifying both successful strategies as well as gaps in Twitter advocacy research. Relevant articles were obtained via PubMed and Google Scholar searches using the phrases “Twitter advocacy healthcare,” “[specialty name] Twitter” and “[specialty name] Twitter advocacy.” Several overarching themes were found to be widely utilized in specialty-specific discussions of Twitter advocacy efforts: organizing under a specific hashtag, fostering dialogue between stakeholders, and tweeting using personalized, action-oriented language. Fields such as pediatrics, heme/onc, ENT, and ophthalmology have most thoroughly embraced the desire to learn how to most effectively advocate on Twitter. Other fields such as OBGYN, cardiology, and surgery have less academic focus on online advocacy. Outside of advocacy efforts, the research and academic benefits of Twitter are well described in nearly every specialty. In conclusion, while clinicians are encouraged to advocate online, only broad strategies for online engagement are currently offered. Additional research into the details of how to successfully create an online profile and Twitter presence is needed to ensure all physicians are able to maximize their advocacy efforts, with clarification of the goals and objectives of this engagement also required.

show abstract

Hematology on Twitter

Abstract: This article has been peer reviewed and published immediately upon acceptance.It is an open access article, which means that it can be downloaded, printed, and distributed freely, provided the work is properly cited.

Cited by 5 publications

References 12 publications

The incidence and clinical spectrum of vincristine- induced peripheral neuropathy in patients with acute lymphoblastic leukemia- a prospective study of twenty-nine cases

The incidence and clinical spectrum of vincristine- induced peripheral neuropathy in patients with acute lymphoblastic leukemia- a prospective study of twenty-nine cases

CAR-T Cells

A Scoping Review of Physician Advocacy on Twitter

Contact Info

Product

Resources

About