Hematomas cerebelosos. Descripción de una cohorte y pronóstico en función de la actitud terapéutica

Virgós-Señor, B.; Nebra-Puertas, A.C.; Villagrasa-Compaired, J.; Popta, J. Van

doi:10.1016/s0210-5691(06)74454-0

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“…Cerebellar hemorrhage (CH) is the least common form of ICH (5–13% of all ICH), but arguably the most lethal (mortality rate of 20–75%) because of its unique neurological location near the brainstem [ 3 ]. Prognostic factors including larger hematoma volumes or diameter, a Glasgow Coma Scale (GCS) ≤8, and imaging findings that reveal the presence of hydrocephalus, intraventricular hemorrhage (IVH), brainstem compression, or basal cistern obligation, for poor outcome [ 4 – 11 ] or early mortality [ 4 , 8 , 12 ] have been reported in patients with CH. However, these studies primarily focus on clinical and imaging findings.…”

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confidence: 99%

Platelet Count and Early Outcome in Patients with Spontaneous Cerebellar Hemorrhage: A Retrospective Study

et al. 2015

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IntroductionThe importance of coagulation, hematology, and biochemical variables have been investigated in the stroke population but have not been systemically surveyed in cerebellar hemorrhage (CH) population. The aim of the study was to explore the predictive value of these factors for early outcome in this population.Materials and MethodsEighty patients with acute spontaneous CH were retrospectively analyzed. Clinical and laboratory data were collected on admission for analysis. The patients were divided by Glasgow outcome scale (GOS) score at discharge into the good outcome group (GOS score 4 or 5) and the poor outcome group (GOS score 1, 2, or 3). The association between early outcome and clinical or laboratory variables were investigated by binary logistic regression.ResultsThere were 46 (57.5%) patients in the poor outcome group and 34 (42.5%) in the good outcome group. The platelet count (PC) was significantly lower in the poor outcome group (187.3 ± 53.0 × 109/l) compared with good outcome group (244.9 ± 63.9 × 109/l) (p < 0.001). Moreover, PC (OR 0.97; p = 0.004) was the strong predictor with poor early outcome.ConclusionsWe firstly show that lower PC is the independent predictor for poor early outcome in patients with spontaneous CH.

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