Hemiparetic cerebral palsy: clinical data compared with neuroimaging

Souza, RC Turolla de; Ciasca, SM; Moura-Ribeiro, Maria Valeriana Leme de; Zanardi, Verônica A.

doi:10.1590/s1413-35552006000200004

Cited by 1 publication

(5 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Whereas others used the number of correct responses out of a possible maximum of ten (28), nine (27,40), five (29), six (37), or three objects(nickel, key, paperclip) (31-33). Two other studies did not include a detailed description of the stereognosis assessment (38,39).…”

Section: General Resultsmentioning

confidence: 99%

“…Patients with lesions in only one brain structure have a better performance on proprioceptive tests compared to those with two or more damaged structures and lesions larger than 10 mm. Patients with unilateral or bilateral cortical and subcortical impairment have more sensory deficits (position sense, as well as tactile perception and registration tests) than patients with subcortical lesions (38).…”

Section: Proprioception Lesion Characteristicsmentioning

confidence: 96%

“…Patients with lesions in the corpus callosum and caudate have a more severe deficit on 2PD tests (27). In addition, larger lesions in these areas correlated with more severe deficits on 2PD and stereognosis tests (37,38).…”

Section: Tactile Perception Lesion Characteristicsmentioning

confidence: 98%

“…Hence the classification into "lesion characteristics" and "functional connectivity" has been discarded Feys et al reported normal touch sensation in all children with PVL-type lesions, compared to approximately 75% of the children with corticalsubcortical brain lesions (7). Touch sensation could be significantly predicted by lesion timing, lesion location, and lesion extent (37,38). In patients with PVL-type lesions, injury severity in thalamocortical pathways is related to sensation of touch (30,37).…”

Section: Tactile Registrationmentioning

confidence: 99%

“…There is substantial evidence that patients with PVL-type lesions have significantly less sensory deficits as opposed to patients with cortical-subcortical/MCA-type lesions (7,27,28,31,32,34,37,38,41). Lesion extent, type of CST wiring pattern, and lesion location significantly further impact sensory function (7,37).…”

Section: Generalmentioning

confidence: 99%

See 4 more Smart Citations

Neuro-imaging characteristics of sensory impairment in cerebral palsy; a systematic review

Knijnenburg

Steinbusch

Janssen-Potten

et al. 2023

Front. Rehabil. Sci.

View full text Add to dashboard Cite

BackgroundObjective: To identify and examine neural reorganization of the sensory network in terms of lesion type, somatotopic organization of the primary somatosensory area, and functional connectivity in relation to sensory function in children and young adults with cerebral palsy (CP).MethodsDesign: systematic review, Prospero registration ID 342570. Data sources: PubMed; Cochrane; Web of Science; Embase; CINAHL and PEDro from inception to March 13, 2021. Eligibility criteria: All types of original studies, concerning sensory connectivity in relation to sensory outcome in patients with spastic CP, <30 years of age. No publication status or date restrictions were applied. Data extraction and synthesis: Two authors independently determined the eligibility of studies. Quality assessment was performed by a third author. Neuro-imaging/neurophysiological techniques, sensory outcomes and patient characteristics were extracted.ResultsChildren and young adults with periventricular leucomalacia (PVL) lesions have significantly better hand function and sensation scores than patients with cortical-subcortical/middle cerebral artery (MCA) lesions. Ipsilesional reorganization of the S1 (primary somatosensory cortex) area appears to be the primary compensation mechanism after a unilateral early brain lesion, regardless of the timing of the lesion. Interhemispheric reorganization of the sensory system after early brain lesions is rare and, when it occurs, poorly effective. Diffusion tractography shows a positive correlation between the ascending sensory tract (AST) diffusivity metrics of the more affected hemisphere and sensory test outcomes.Discussion and conclusionsBecause of the large variability in study design, patient characteristics, neuroimaging/neurophysiological techniques and parameters as well as sensory assessment methods used, it is difficult to draw definite inferences on the relationship between the reorganization of the sensory network following early brain damage and sensory function in children and young adults with CP. In general, sensory function seems to be worse in cortical as opposed to white matter tract (PVL) lesions. International consensus on a clinically relevant sensory test battery is needed to enhance understanding of the intriguing compensatory mechanisms of sensory network following early brain damage and potential consequences for rehabilitation strategies.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/.

show abstract