Hemochromatosis of the pituitary gland: MR imaging.

Abstract

Magnetic resonance imaging of the pituitary gland in a patient with secondary hemochromatosis is described. On T1-weighted images, the anterior lobe had almost no signal intensity, and only the high-signal posterior lobe was seen. These findings are compatible with the distribution of iron deposition and clinical symptoms in hemochromatosis.

Hypoparathyroidism and Subclinical Hypothyroidism with Secondary Hemochromatosis

“…Gonadotropin deficiency commonly includes the entire pituitary hormone, resulting in impotency, menstrual irregularities, and decreased libido [9]. Siderosis can also cause functional failures in the adrenal, parathyroid, and thyroid, although these issues are less common than diabetes or gonadotropin deficiency [10,11].…”

Iron Deposition in the Anterior Pituitary in Homozygous Beta-Thalassemia: MRI Evaluation and Correlation with Gonadal Function

“…2, 2000 Brought to you by | University of Arizona Authenticated Download Date | 5/28/15 7:13 PM 10 . MRI has been used for iron quantification in the brains of patients with Parkinson's disease VOLUME 13, NO.…”

Transfusional Hemochromatosis: Quantitative Relation of MR Imaging Pituitary Signal Intensity Reduction to Hypogonadotropic Hypogonadism

“…Findings of a number of studies have shown that by exploiting such superparamagnetic effects pituitary iron deposition can be demonstrated with MR imaging in the form of a reduction of signal intensity in the anterior lobe (12)(13)(14)(15). Gradient-echo (GRE) T2*-weighted imaging has been shown to be the most sensitive sequence for detecting excess pituitary iron deposition (16).…”