Hemocompatible poly(lactic acid) membranes prepared by immobilizing carboxylated graphene oxide via mussel-inspired method for hemodialysis

Abstract

Carboxylated graphene oxide modified PLA membrane via mussel-inspired method exhibited excellent hemocompatibility and dialysis performance.

Antiblood Cell Adhesion of Mussel-Inspired Chondroitin Sulfate- and Caffeic Acid-Modified Polycarbonate Membranes

“…The maximum reduced zeta potential was achieved in the case of the CA-CS-PC-2 membrane. These results were similar to the results obtained in the SEM images because the highest coating of adhesive polymer might be the reason for the reduction in the zeta potential. , In addition, the zeta potential measurement at various pH values (Figure b) proved that the increased pH influenced the zeta potential of the membrane substrate. All the CA-CS-modified polymers exhibit positive zeta potential at pH 2, because of the protonation of −COOH and OH in CA-PC and −COOH, OH, and NH 2 in CA-CS-modified membranes.…”

“…In 2020, Huang et al reported PDA and PEI modified layer-by-layer assembly on polycarbonate (PC) membranes with the antiadhesion property of microalgae harvesting . Ma et al reported PDA- and GO-modified PLA hemocompatible membranes for hemodialysis . Caffeic acid is another mussel-inspired material that is a naturally abundant polyphenol that has recently attracted much attention, because of its thin-film forming and modification of various substrates for reduced adhesion applications .…”

Nano architectured cues as sustainable membranes for ultrafiltration in blood hemodialysis

“…Many researchers had worked on the modification of the membrane by using different polymers along with additives to optimize the rejection capabilities. Different varieties of polymers that were used are cellulose acetate (CA), polysulfone (PSU) [4], polyethersulfone (PES) [5], polymethyl methacrylate (PMMA), polyacrylonitrile (PAN) [6], polyvinyl alcohol (PVA) [7], polylactic acid (PLA), polypropylene (PP), polyamide, chitosan, here every polymer had different abilities in terms of biocompatibility and performance efficiency [8]. PSU is considered the best base polymer because it contains the best mechanical, chemical property and processability.…”

Graphene Oxide Coating Improves the Mechanical and Biological Properties of Decellularized Umbilical Cord Arteries

“…Wilczek et al did not find a significant difference in platelet activation and adhesion upon reduced graphene oxide (rGO) coating of decellularized heart valves, but this can be justified by the higher hydrophilicity of GO compared to rGO, since low-fouling features are associated with hydrophilic surfaces, as shown for GO and rGO free-standing films . Despite not being present in decellularized matrices, GO coatings also showed a successful effect in decreasing platelet adhesion to other biomaterial surfaces, such as titanium, electrospun fibroporous polycarbonate urethane, nitinol, polyether-sulfone hollow fiber membranes, and poly­(lactic acid) …”

“…56 Despite not being present in decellularized matrices, GO coatings also showed a successful effect in decreasing platelet adhesion to other biomaterial surfaces, such as titanium, 52 electrospun fibroporous polycarbonate urethane, 57 nitinol, 53 polyethersulfone hollow fiber membranes, 58 and poly(lactic acid). 59 Infection is a common failure cause to all implantable devices, and vascular grafts are not an exception. 60 In this study, we show that decellularized matrices adhered high amounts of S. aureus, one of the most prevalent infection agents for vascular grafts.…”