Hemodialysis and peritoneal dialysis—health-related quality of life: systematic review plus meta-analysis

Abstract

BackgroundPatients with end-stage renal disease undergoing haemodialysis experience a variety of stressors leading to decreased level of quality of life (QoL). Thus, in this study, we aimed to review the current literature and identify factors affecting the health-related QoL (HRQoL) in these patients.MethodsA total of 147 studies were extracted from databases of Web of Science, PubMed, Scopus, Google Scholar, and Embase published between January 2000 and December 2020. Data were analysed using R software and results were reported with reference to Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards.ResultsA total of 623 728 patients undergoing dialysis participated in 147 studies in which QoL was assessed by means of two valid questionnaires, including Short-Form 36 (SF-36) and Kidney Disease Quality of Life (KDQOL)-short form V.1.3. Total HRQoL score for patients undergoing dialysis measured by KDQOL was 64.25 (95% CI 55.67 to 72.82). Based on SF-36, the mean score of mental health items was higher than the mean score of physical health condition. Furthermore, meta-regression based on the geographical place of residence revealed that the highest QoL in patients was observed in Japan, 66.96 (95% CI 63.65 to 70.28) and Brazil, 58.03 (95% CI 53.45 to 62.6).ConclusionStudies conducted on HRQoL among patients undergoing dialysis recommend useful strategies to clinicians, letting them assess patients’ QoL in terms of a wide range of physical, mental and environmental aspects.

Epidemiology of peritoneal dialysis outcomes

“…For instance, the SONG-PD group found that 76% of studies reported both dimensions; an additional 14% and 10% of studies reported obligatory and non-obligatory dimensions, respectively 24 . Patients receiving PD often have a better employment status than those treated with HD 106 – 110 , probably because they need to spend less time in a treatment facility. One study reported that PD was associated with a 4% increased probability of employment, 6% reduced probability of disability pension requirement and increased work income compared with HD 111 .…”

“…The ChinaQ study randomly assigned 725 patients across China to PD or HD and found that the burden of kidney disease on the PD group was non-inferior to that of the HD group 112 . However, studies comparing QOL between patients receiving HD or PD have tended to show better QOL in PD than in HD 108 – 110 . This difference might result from greater lifestyle flexibility, better ability to perform exchanges at home (or in a comfortable place that imposes less restriction), and better dietary flexibility in patients receiving PD 110 .…”

“…However, studies comparing QOL between patients receiving HD or PD have tended to show better QOL in PD than in HD 108 – 110 . This difference might result from greater lifestyle flexibility, better ability to perform exchanges at home (or in a comfortable place that imposes less restriction), and better dietary flexibility in patients receiving PD 110 .…”

Association Between Exercise Self-Efficacy and Health-Related Quality of Life Among Dialysis Patients: A Cross-Sectional Study

“…A recent meta-analysis involving 147 studies reported a pooling mean HRQOL score for patients undergoing dialysis as 64.25 [95% confidence interval (CI): 55.67–72.82] ( Raoofi et al, 2021 ). In the present study, the overall mean score of HRQOL was modestly lower than the results mentioned above.…”

Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice?

“…Compared to ICHD, PD gives the opportunity to dialyze at home, independently or with the help of a caregiver. Additionally, the short amount of time required for fluid exchange allows a flexible schedule and the opportunity to work, travel or participate in recreational activities [179][180][181]. Using the KDQOL SF 1.3, Wakeel et al compared the QoL of 200 patients on ICHD or PD in Saudi Arabia.…”