Hemodynamic and Prognostic Implications of Net Atrioventricular Compliance in Patients with Mitral Stenosis

Kim, Yong Jin; Hwang, Seok Jae; Park, Jin Shik; Chang, Hyuk Jae; Oh, Byung Hee; Park, Young Bae

doi:10.1016/j.echo.2007.08.024

Cited by 27 publications

(30 citation statements)

References 12 publications

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“…A previous study13 with 26 patients evaluated the relation between C n and clinical events and found that low left atrial C n predicted the need for MV intervention. Subsequently, we demonstrated that C n was an important predictor of MV intervention,18 adding incremental prognostic value to clinical data and MV area.…”

Section: Discussionmentioning

confidence: 99%

Net atrioventricular compliance is an independent predictor of cardiovascular death in mitral stenosis

Nunes

Tan

Elmariah

et al. 2017

Heart

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Section: Discussionmentioning

confidence: 99%

Net atrioventricular compliance is an independent predictor of cardiovascular death in mitral stenosis

Nunes

Tan

Elmariah

et al. 2017

Heart

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“…Interestingly, LA stiffness in our study accounted well for the observed PA systolic pressure quite similar to the findings in patients with mitral stenosis where LA compliance related well to symptomatic status, PA pressures at rest and exercise, and subsequent need for percutaneous or surgical intervention. 23,24 Furthermore, a recent report noted significant correlations between PA systolic pressure and mean PCWP. 25 Although LA structure was not examined in this investigation, a previous canine study in a model with LV DD has shown the association of increased LA stiffness with LA hypertrophy and upregulation of the ␤-myosin heavy chain isoform.…”

Section: La Diastolic Function In Dhfmentioning

confidence: 97%

Left Atrial Function in Diastolic Heart Failure

Kurt

Wang

Torre‐Amione

et al. 2009

Circ: Cardiovascular Imaging

428

317

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Background-Abnormalities in left ventricular (LV) structure and function occur in patients with diastolic heart failure (DHF). The reasons for the transition from asymptomatic dysfunction to heart failure need better definition, including noninvasive measurements that can detect the transition. Methods and Results-In 64 patients undergoing right heart catheterization, simultaneous echocardiographic imaging was performed. As a control group, 27 healthy subjects were included. There were 25 with ejection factor (EF) Ͻ50%, 20 in DHF, and 19 with normal EF and LV hypertrophy but not in heart failure (diastolic dysfunction). LV volumes, mass, left atrial (LA) volumes and EF, annular atrial velocity (aЈ), and LA strain during systole (LA S ), and atrial contraction (LA A ) were measured. The ratio of wedge pressure to LA S strain was used as an index of LA stiffness, as was the ratio of E/eЈ to LA S strain. All 3 patient groups had increased LA volumes and depressed LA EF, aЈ, and LA A strain, with no significant difference between patients with DHF and diastolic dysfunction in LA systolic function indices, LV mass, LA volumes, LV, and arterial elastance. LA S strain was lower in patients with DHF, and LA stiffness (invasive and noninvasive) was higher (both PϽ0.01), related well to pulmonary artery systolic pressure (rϭ0.79, PϽ0.001), and was most accurate in identifying DHF patients from those with diastolic dysfunction (invasive area under the curve: 0.93, noninvasive: 0.85). Conclusions-Patients

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“…Reduced compliance (mitral valve area/mitral E wave down slope Ͻ 4 ml/mm Hg) predicted the need for mitral valve replacement or commissurotomy and defined a mitral stenosis cohort in which PH was closely linked to functional capacity. 40 PH is prognostically powerful in the natural history of mitral valve disease. In a multi-center registry of degenerative mitral regurgitation, an echocardiographically derived PASP Ͼ 50 mm Hg (present in 23%) was an independent predictor of death, cardiovascular death, and HF during a mean follow-up of 4 years.…”

Section: Mitral Valve Diseasementioning

confidence: 99%

World Health Organization Pulmonary Hypertension Group 2: Pulmonary hypertension due to left heart disease in the adult—a summary statement from the Pulmonary Hypertension Council of the International Society for Heart and Lung Transplantation

Fang

DeMarco

Givertz

et al. 2012

The Journal of Heart and Lung Transplantation

215

194

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Hemodynamic and Prognostic Implications of Net Atrioventricular Compliance in Patients with Mitral Stenosis

Cited by 27 publications

References 12 publications

Net atrioventricular compliance is an independent predictor of cardiovascular death in mitral stenosis

Net atrioventricular compliance is an independent predictor of cardiovascular death in mitral stenosis

Left Atrial Function in Diastolic Heart Failure

World Health Organization Pulmonary Hypertension Group 2: Pulmonary hypertension due to left heart disease in the adult—a summary statement from the Pulmonary Hypertension Council of the International Society for Heart and Lung Transplantation

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