Hemodynamic Evaluation of HeartWare MVAD in Normal and Infarct Swine Models

Pham, Duc T.; Paruchuri, Vikram; Esposito, Michele; Schraufnagel, Dean P.; McSparren, D.; Civiello, D.; Todd-Elliot, V.; Vassallo, C.; Murphy, Barbara F.; Reyelt, Lara; Beale, Corinna; Tamez, Daniel; Nuñez, Nilsa; Voskoboynikov, Neil; Kapur, N.K.

doi:10.1016/j.healun.2013.01.445

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For instance, such devices as: self‐driving aortic‐turbine venous‐assist device, cavopulmonary microaxial pump or artificial right ventricular have shown to provide positive short‐term outcomes in Fontan patients. One of the possible decisions for the MCS of the patient with failing Fontan is miniature rotary blood pumps, such as Jarvik 2015 or MVAD . These pumps due to their size can anatomically fit to patients with a univentricular heart.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Energetics of blood flow in Fontan circulation under VAD support

et al. 2019

View full text Add to dashboard Cite

The need to simulate the normal operating conditions of the human body is the key factor in every study and engineering process of bioelectronic devices designed for implantation. The Fontan procedure is an example of such a process aimed to support the human body function. It is a standard treatment method for patients with a functionally univentricular heart. However, it has significant drawbacks such as overload of the only functional heart ventricle that often leads to the necessity of the heart transplantation. In this study, we analyze the total cavopulmonary connection (TCPC) influence on the blood with and without connected auxiliary blood circulation pump. We investigate four different types of TCPC configurations, analyze blood pressure and different flow rate, study the turbulent kinetic energy distribution, and evaluate hydraulic and power losses for various cases. Finally, we calculate volumetric scalar shear stresses distribution and demonstrate the high potential of TCPC configuration with connected rotary pump as a tool for the load redistribution in the functional heart ventricle. This work is particularly relevant for improving existing TCPCs’ quality that can extend the life of Fontan patients. Moreover, it also applies to the reduction of morbidity and mortality of the patients waiting for the heart transplantation.

show abstract

Section: Introductionmentioning

confidence: 99%

“…One of the possible decisions for the MCS of the patient with failing Fontan is miniature rotary blood pumps, such as Jarvik 2015 16 or MVAD. 17 These pumps due to their size can anatomically fit to patients with a univentricular heart.…”

Section: Introductionmentioning

confidence: 99%