Hemodynamic Parameters of Low-Flow Isoflurane and Low-Flow Sevoflurane Anesthesia During Controlled Ventilation With Laryngeal Mask Airway

Peirovifar, Ali; Mahmoodpoor, Ata; Parish, Masoud; Golzari, Samad Ej; Molseqi, Haniye; Negargar, Sohrab

doi:10.5812/aapm.20326

Cited by 6 publications

(5 citation statements)

References 26 publications

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“…This is associated with good hemodynamic stability and high patient acceptance. [ 10 ] Administration of fentanyl before LMA insertion gives synergistic effect with propofol and sevoflurane. [ 11 ]…”

Section: Discussionmentioning

confidence: 99%

Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures

Chavan

Gujar

Shinde

2017

J Anaesthesiol Clin Pharmacol

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Background and Aims:A popular method of providing anesthesia for laryngeal mask airway (LMA) insertion is with the use of propofol. However, bolus propofol has been associated with adverse effects such as hypotension, apnea and pain on injection. Hence, time is needed to search an alternative. We aimed to compare the induction characteristics, ease of LMA insertion, hemodynamic changes and complications with inhalation of 8% sevoflurane vital capacity breath and propofol.Material and Methods:A prospective randomized study of 60 American Society of Anesthesiologists' Grade I and II patients was conducted and distributed among two groups with 30 each undergoing gynecological procedures under general anesthesia. Group P received the injection propofol and Group S received sevoflurane. At the end point of induction, the LMA insertion was attempted. Scoring systems were used to grade the conditions for insertion of the LMA. Induction, LMA insertion characteristics, hemodynamic changes, complications were assessed. Data were recorded and analyzed. Comparison among the study groups was done with unpaired t-test, Mann–Whitney test and Chi-square test.Results:Sevoflurane took a longer time for induction and for LMA insertion than propofol. There was no statistically significant difference between the two groups, with respect to LMA insertion characteristics, heart rate, mean arterial pressure. It is concluded that sevoflurane is associated with good hemodynamic stability and may prove useful incases where propofol is to be avoided. However, the ease of insertion provided with propofol is better.

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Section: Discussionmentioning

confidence: 99%

Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures

Chavan

Gujar

Shinde

2017

J Anaesthesiol Clin Pharmacol

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“…Regarding the hemodynamic parameters, Negargar et al [21], in their study DAP, SAP and MAP in the sevoflurane group were significantly lower than the isoflurane group. This might have been due to the effect of sevoflurane on cardiorespiratory reflexes.…”

Section: ! "#$%And!'(!)and*+-#/01!2#3#!+4!3/and!#30and536!#52!27-#30+5!+4!67-and-8! ! 96+4%7-#5and!:-+7!! ;5!<!'=>! ?And@+4%7-#5and!:-+7!mentioning

confidence: 84%

“…The direct vasodilator effect of sevoflurane is considered to be 20% of isoflurane. This weak and vasodilator effect of sevoflurane may help explain why cerebral vasculature remains stable in response to changes in CPP during anaesthesia of sevoflurane, but this is disturbed due to extensive cerebral vasodilatation in isoflurane anaesthesia at the same concentration [21]. In addition, because of this weak vasodilation effect, sevoflurane is likely to cause a marked increase in ICP.…”

Section: ! "#$%And!'(!)and*+-#/01!2#3#!+4!3/and!#30and536!#52!27-#30+5!+4!67-and-8! ! 96+4%7-#5and!:-+7!! ;5!<!'=>! ?And@+4%7-#5and!:-+7!mentioning

confidence: 99%

Comparison of neuroprotective effect of isoflurane and sevoflurane on cerebral ischemia

Sayan

Erdem²,

Korfali

2020

The European Research Journal

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P atients undergoing intracranial surgery are at risk for cerebral ischemia. Therefore, the aim of neuro-anaesthetics is to provide adequate cerebral perfusion during surgery [1]. In patients with increased intracranial pressure (ICP), due to cerebral tumors it is accepted that volatile anaesthetic agents are effective in the protection of cerebral ischemia that may develop due to decrease in systolic arterial pressure (SAP) [2]. Isoflurane's cerebral protection mechanisms include reduction of cerebral metabolic rate (CMR) and metabolic suppression, inhibition of sympathetic activity, reduction of glutamate receptors which are prevent calcium flow, and suppression of excitotoxicity of calcium cascade [3]. It is thought that isoflurane may be secondary to direct vasodilatation or to reduction in CMR by the increase in cerebral blood flow (CBF) reduction [4]. Isoflurane has been reported to cause cerebral protection similar to barbiturates by depressing CMR, and it was shown that it reduce ceree

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“…Deepak singh et al ( 2009), [11] concluded that none of the patients demonstrated any haemodynamic instability that required use of rescue drug in Sevoflurane or Isoflurane group. Sohrab negarkar et al (2014), [10] observed that there was increase in SBP in Isoflurane group at 10min, 15min and 30 min than Sevoflurane group which was statistically significant. There was increase in DBP in Isoflurane group at 10 min and 30 min than Sevoflurane group which was statistically significant.…”

Section: Systolic Blood Pressure (Sbp) and Diastolic Blood Pressure (...mentioning

confidence: 88%

“…During Isoflurane anaesthesia, tachycardia may be better controlled with the intermittent use of narcotics which is not used in our study. Sohrab negarkar etal (2014), [10] observed that the mean heart rate was more in Isoflurane group than Sevoflurane group at 25 min(p>0.05). However, the mean heart rate was comparable between the two groups during the study period.…”

Section: Heart Ratementioning

confidence: 93%

Comparative Study of Maintenance and Recovery Characteristics of Sevoflurane and Isoflurane in Neurosurgery

Vali¹,

Khobragade²

2019

AAN

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Background: Rapid recovery is very important in neurosurgical patients for early neurological assessment. The purpose of this study was to compare the maintenance and recovery characteristics of two most commonly used volatile anaesthetic agents, Isoflurane and Sevoflurane in neurosurgery patients. Subjects and Methods: A hospital based, prospective, randomized, comparative study was undertaken in tertiary care centre for a period of two years after institutional ethical committee approval. The study included 60 patients undergoing neurosurgical surgeries in general anaesthesia. After intravenous induction, maintenance was achieved by inhalational anaesthetic agent according to randomly allocated group. Haemodynamic parameters like heart rate, systolic blood pressure, diastolic blood pressure along with recovery time and complications were studied and p<0.05 was considered significant on statistical analysis. Results: The pulse rate was significantly less in sevoflurane group than isoflurane group from 20 min to 120 min (p<0.05). The mean systolic and diastolic blood pressure were comparable in both the groups except the systolic and diastolic blood pressure were lower in Sevoflurane group than Isoflurane group at 5 min(p<0.05). The mean emergence time and extubation time were significantly shorter in Sevoflurane group than Isoflurane group(p<0.001). Conclusion: Sevoflurane provides stable haemodynamics during maintenance of anaesthesia and allows rapid recovery for faster postoperative basic neurological assessment.

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Hemodynamic Parameters of Low-Flow Isoflurane and Low-Flow Sevoflurane Anesthesia During Controlled Ventilation With Laryngeal Mask Airway

Cited by 6 publications

References 26 publications

Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures

Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures

Comparison of neuroprotective effect of isoflurane and sevoflurane on cerebral ischemia

Comparative Study of Maintenance and Recovery Characteristics of Sevoflurane and Isoflurane in Neurosurgery

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