Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle

Liu, Ming; Sun, Anqiang; Deng, Xiaoyan

doi:10.1186/s12938-018-0517-1

Cited by 8 publications

(7 citation statements)

References 31 publications

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“…Additionally, the high OSI area, which decreased with the increase in the aneurysm neck angle in a proportional manner, was mainly concentrated at the proximal end of the iliac limb SGs. High OSI area was reported to cause platelet aggregation, increase the retention time of coagulation-promoting particles and result in thrombosis ( Nordgaard et al, 2010 ; Liu et al, 2018 ). Therefore, we speculate that there may be a risk of thrombosis in the proximal end of the iliac limb SGs.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, the neck angulation may be coronal and/or sagittal; namely, the hemodynamic alteration from a conventional non-cross EVAR may be caused by different spatial azimuths. However, previous hemodynamic studies on the cross and non-cross EVAR mostly adopted idealized and realistic models without neck angulation ( Georgakarakos et al, 2014 ; Stefanov et al, 2016 ; Liu et al, 2018 ). Moreover, although there have been comparative studies using patient-specific EVAR models in which necks may be angulated, a particular AAA has individualized geometry, and other geometric features (including the stent configuration) may cause the hemodynamic differences between the cross and non-cross SGs ( Efstratios, 2012 ; Stefanov et al, 2016 ).…”

Section: Introductionmentioning

confidence: 99%

“…Some researchers have suggested that cross and non-cross EVAR demonstrate similar hemodynamic performance, and a cross limb configuration may even inhibit the thrombosis formation because it increases the wall shear stress (WSS) and helicity ( Shek et al, 2012 ). Nevertheless, some studies have suggested that cross-limb configurations might result in strip areas vulnerable to thrombosis formation, potentially resulting in long-term stent graft failure ( Liu et al, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

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A Comparative Study on the Hemodynamic Performance Within Cross and Non-cross Stent-Grafts for Abdominal Aortic Aneurysms With an Angulated Neck

et al. 2021

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Objectives: Cross-limb stent grafts for endovascular aneurysm repair (EVAR) are often employed for abdominal aortic aneurysms (AAAs) with significant aortic neck angulation. Neck angulation may be coronal or sagittal; however, previous hemodynamic studies of cross-limb EVAR stent grafts (SGs) primarily utilized simplified planar neck geometries. This study examined the differences in flow patterns and hemodynamic parameters between crossed and non-crossed limb SGs at different spatial neck angulations.Methods: Ideal models consisting of 13 cross and 13 non-cross limbs were established, with coronal and sagittal angles ranging from 0 to 90°. Computational fluid dynamics (CFD) was used to capture the hemodynamic information, and the differences were compared.Results: With regards to the pressure drop index, the maximum difference caused by the configuration and angular direction was 4.6 and 8.0%, respectively, but the difference resulting from the change in aneurysm neck angle can reach 27.1%. With regards to the SAR-TAWSS index, the maximum difference caused by the configuration and angular direction was 7.8 and 9.8%, respectively, but the difference resulting from the change in aneurysm neck angle can reach 26.7%. In addition, when the aneurysm neck angle is lower than 45°, the configuration and angular direction significantly influence the OSI and helical flow intensity index. However, when the aneurysm neck angle is greater than 45°, the hemodynamic differences of each model at the same aneurysm neck angle are reduced.Conclusion: The main factor affecting the hemodynamic index was the angle of the aneurysm neck, while the configuration and angular direction had little effect on the hemodynamics. Furthermore, when the aneurysm neck was greatly angulated, the cross-limb technique did not increase the risk of thrombosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A Comparative Study on the Hemodynamic Performance Within Cross and Non-cross Stent-Grafts for Abdominal Aortic Aneurysms With an Angulated Neck

et al. 2021

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“…The no-slip condition was imposed on the surface of the models according to the rigid wall assumption [ 28 ]. It was shown that the maximum DF and peak pressure drop arose at peak pressure throughout the cardiac cycle [ 29 , 30 ]. As a result, a constant velocity of v = 0.1 m/s was applied at the inlets, and the pressure was set as 105 mmHg at the outlets, which characterized the moment of peak pressure throughout the cardiac cycle [ 31 ].…”

Section: Methodsmentioning

confidence: 99%

Fast and Accurate Computation of the Displacement Force of Stent Grafts after Endovascular Aneurysm Repair

Qing

Zheng

2022

Bioengineering

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Purpose: Currently, the displacement force of stent grafts is generally obtained using computational fluid dynamics (CFD), which requires professional CFD knowledge to perform the correct simulation. This study proposes a fast, simple, and clinician-friendly approach to calculating the patient-specific displacement force after endovascular aneurysm repair (EVAR). Methods: Twenty patient-specific post-EVAR computed tomography angiography images were used to reconstruct the patient-specific three-dimensional models, then the displacement forces were calculated using CFD and the proposed approaches, respectively, and their numerical differences were compared and analyzed. Results: Based on the derivation and simplification of the momentum theorem, the patient-specific displacement forces were obtained using the information of the patient-specific pressure, cross-sectional area, and angulation of the two stent graft ends, and the average relative error was no greater than 1.37% when compared to the displacement forces calculated by CFD. In addition, the linear regression analysis also showed good agreement between the displacement force values calculated by the new approach and CFD (R = 0.999). Conclusions: The proposed approach can quickly and accurately calculate the patient-specific displacement force on a stent graft and can therefore help clinicians quickly evaluate the post-EVAR displacement force.

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“…C o m p u t e r-b a s e d s i m u l a t i o n h a s b e e n u s e d t o generate three-dimensional (3D) models and clarify the hemodynamics in patients with brain aneurysms, coronary artery aneurysms, and abdominal aortic aneurysms, among other conditions (9)(10)(11). However, it has not been used in ocular diseases.…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional ophthalmic artery model reconstruction and assessment captured by computed tomographic angiography in non-arteritic anterior ischemic optic neuropathy patients

Wang

et al. 2021

Ann Transl Med

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Background: The ophthalmic artery (OA) was first reconstructed using computer software. The structural differences of ophthalmic arteries in non-arteritic anterior ischemic optic neuropathy (NAION) and normal eyes, in addition to hemodynamic alterations, were assessed.Methods: Thirty-one NAION eyes, 19 uninvolved eyes with NAION, and a control group of 26 healthy eyes were retrospectively included. Computed tomographic angiography data were recorded, and corresponding three-dimensional OA models were constructed. Initial OA and internal carotid artery (ICA) diameters and the angle between them were analyzed. Three different OA models were used to evaluate hemodynamic performance. The statistical relationships between the initial diameters of the OA and ICA and the angle between the OA and ICA were described.Results: OA diameters in NAION eyes were significantly smaller than those in both uninvolved and healthy eyes (P<0.05). There was no significant difference between uninvolved and healthy eyes (P=0.31).The initial ICA diameter and the angle between the OA and ICA did not significantly differ among the three groups. In the three models, the blood flow velocity in the initial ophthalmic arteries of uninvolved eyes was higher than that in the NAION eyes. The mass flows of the right and left ophthalmic arteries, accounting for the ipsilateral ICA in the control model, were 0.57%. However, these values in uninvolved and NAION eyes were 1.36% and 0.25%, respectively.Conclusions: NAION is associated with a smaller initial OA diameter, which may be related to hypoperfusion. To our knowledge, this is the first pilot study to analyze hemodynamic alterations using OA models.

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Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle

Cited by 8 publications

References 31 publications

A Comparative Study on the Hemodynamic Performance Within Cross and Non-cross Stent-Grafts for Abdominal Aortic Aneurysms With an Angulated Neck

A Comparative Study on the Hemodynamic Performance Within Cross and Non-cross Stent-Grafts for Abdominal Aortic Aneurysms With an Angulated Neck

Fast and Accurate Computation of the Displacement Force of Stent Grafts after Endovascular Aneurysm Repair

Three-dimensional ophthalmic artery model reconstruction and assessment captured by computed tomographic angiography in non-arteritic anterior ischemic optic neuropathy patients

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