Hemodynamic, renal, and hormonal responses to brain natriuretic peptide infusion in patients with congestive heart failure.

Yoshimura, Michihiro; Yasue, Hirofumi; Morita, Eugene Hayato; Sakaino, Naritsugu; Jougasaki, Michihisa; Kurose, Mitsuro; Mukoyama, Masashi; Saito, Yoshihiko; Nakao, Kazuwa; Imura, Hiroo

doi:10.1161/01.cir.84.4.1581

Cited by 394 publications

(214 citation statements)

References 45 publications

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“…Furthermore, upper airway obstruction is associated with exaggerated negative intrathoracic pressure swings, increased systemic venous return and preload to the right ventricle along with increased left cardiac ventricle after load (23,24). Acute overload of the cardiac ventricles could promote release of brain natriuretic peptide from ventricular myocytes which induces vasodilation and natriuresis (25). Adenotonsillectomy for OSA in childhood is accompanied by reduction of morning brain natriuretic peptide levels in venous blood (26).…”

Section: Discussionmentioning

confidence: 99%

Nocturnal enuresis is associated with moderate-to-severe obstructive sleep apnea in children with snoring

et al. 2014

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Background: Conflicting data suggest that prevalence of monosymptomatic primary nocturnal enuresis (NE) increases with increasing severity of obstructive sleep apnea (OSA) in childhood and especially in girls. We hypothesized that NE is associated with increased risk of moderate-to-severe OSA (obstructive apnea-hypopnea index (AHI) >5 episodes/hour) among children with snoring. Methods: Data of children (≥5 y old) with snoring who were referred for polysomnography over 12 y were reviewed. results: Data of 525 children with mean age (±SD) 7.5 (± 2.2) y and median obstructive AHI (10th-90th percentiles) 1.9 (0.4-7.3) episodes/hour were analyzed. Three hundred and fifty-five children (67.6%) had NE and 87 (16.6%) had moderate-to-severe OSA. There was no interaction between NE and gender regarding the association with moderate-to-severe OSA (P > 0.05). NE was associated significantly with presence of moderate-to-severe OSA after adjustment for tonsillar hypertrophy, obesity, gender, and age (adjusted odds ratio = 1.92 (1.08-3.43); P = 0.03). Presence of NE had high sensitivity (78.2%) and low positive predictive value (19.2%) for detecting moderate-to-severe OSA and low specificity (34.5%) and high negative predictive value (88.8%) for ruling it out. conclusion: Children with snoring and without NE referred for polysomnography are less likely to have moderate-tosevere OSA compared to those with NE.

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Section: Discussionmentioning

confidence: 99%

Nocturnal enuresis is associated with moderate-to-severe obstructive sleep apnea in children with snoring

et al. 2014

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“…[1][2][3][4][5][6][7] BNP is secreted from the failing heart into the systemic circulation; the plasma level of this peptide is elevated in patients with heart failure. 8 -11 The plasma BNP level has been recognized as a biochemical marker of ventricular dysfunction.…”

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confidence: 99%

Plasma Level of B-Type Natriuretic Peptide as a Prognostic Marker After Acute Myocardial Infarction

et al. 2004

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Background-Circulating levels of B-type natriuretic peptide (BNP), a cardiac hormone, reflect the severity of cardiac dysfunction. Because the plasma BNP level changes dramatically during the period after the onset of acute myocardial infarction (AMI), identification of a suitable sampling time is problematic. There have been several reports indicating that the plasma BNP level obtained in the acute phase of AMI can be used as a prognostic marker. We examined whether the plasma BNP level measured 3 to 4 weeks after the onset of AMI represents a reliable prognostic marker for patients with AMI. Methods and Results-We analyzed 145 consecutive patients with AMI. Plasma BNP levels were measured during the 3 to 4 weeks after onset of AMI. Of those patients, 23 experienced fatal cardiac events during this study. The mean follow-up period was 58.6 months. Log BNP, left ventricular end-diastolic pressure, and pulmonary vascular resistance were all significantly higher in the cardiac death group, and there were more men and more patients with a history of heart failure in the cardiac death group. A Cox proportional hazards model analysis showed that log BNP was an independent predictor of cardiac death. The survival rate was significantly higher in patients with log BNP Ͻ2.26 (180 pg/mL) than in those with log BNP Ն2.26. Conclusions-The plasma BNP level obtained 3 to 4 weeks after the onset of AMI can be used as an independent predictor of cardiac death in patients with AMI.

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“…As the ANF, the brain natriuretic factor seems to play a significant role in the pathophysiology of the CHF, acting as an endogenous vasodilator and diuretic. The clinical improvement observed when it is administered to patients with CHF confirms this hypothesis 109 . Its importance as a prognostic factor was recently demonstrated.…”

Section: Atrial Natriuretic Factor -In 1985 Lang Et Almentioning

confidence: 58%

Prognostic factors in patients with congestive heart failure

Villacorta¹,

Mesquita²

1999

Arq. Bras. Cardiol.

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Hemodynamic, renal, and hormonal responses to brain natriuretic peptide infusion in patients with congestive heart failure.

Cited by 394 publications

References 45 publications

Nocturnal enuresis is associated with moderate-to-severe obstructive sleep apnea in children with snoring

Nocturnal enuresis is associated with moderate-to-severe obstructive sleep apnea in children with snoring

Plasma Level of B-Type Natriuretic Peptide as a Prognostic Marker After Acute Myocardial Infarction

Prognostic factors in patients with congestive heart failure

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