Hemodynamics in humans during conventional and experimental methods of cardiopulmonary resuscitation.

Swenson, Robert; Weaver, W. Douglas; Niskanen, Robert A.; Martin, Jennifer; Dahlberg, Seth T.

doi:10.1161/01.cir.78.3.630

Cited by 126 publications

(27 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Models indicate that the optimum duty cycle for coronary flow is about 30-40%,10 consistent with results observed in humans. 21 The higher coronary flow with 30% duty cycle in our study agrees with this prediction. …”

Section: Intrathoracic Compression Pressures and Chest Geometrysupporting

confidence: 89%

Improved blood flow during prolonged cardiopulmonary resuscitation with 30% duty cycle in infant pigs.

et al. 1991

View full text Add to dashboard Cite

Background. Sustained compression is recommended to maximize myocardial and cerebral blood flow during cardiopulmonary resuscitation (CPR) in adults and children. We compared myocardial and cerebral perfusion during CPR in three groups of 2-week-old anesthetized swine using compression rates and duty cycles (duration of compression/total cycle time) of 100 per minute, 60%; 100 per minute, 30%; and 150 per minute, 30%1.Methods and Results. Ventricular fibrillation was induced and CPR was begun immediately with a sternal pneumatic compressor. Epinephrine was continuously infused during CPR. Microsphere-determined blood flow and arterial and sagittal sinus blood gas measurements were made before cardiac arrest was induced and after 5, 10, 20, 35, and 50 minutes of CPR.

show abstract

Section: Intrathoracic Compression Pressures and Chest Geometrysupporting

confidence: 89%

Improved blood flow during prolonged cardiopulmonary resuscitation with 30% duty cycle in infant pigs.

et al. 1991

View full text Add to dashboard Cite

show abstract

“…One reason for this is that breath-stacking occurs when ventilation is as rapid as typical compression rates. This elevates Ppl and Pra during the release phase [100], and impedes venous return. Such breath-stacking is inevitable despite the forced expiration caused by chest compression, because expiration is flow-limited.…”

Section: Steady-state Effects Positive End-expiratory Pressure and Comentioning

confidence: 99%

Heart-lung interactions: applications in the critically ill

Fessler¹

1997

Eur Respir J

View full text Add to dashboard Cite

Since the circulatory and pulmonary systems are both driven by pressure and share space in the thorax, it is inevitable that they interact. These mechanical interactions, whilst relatively few in number, are protean in their manifestations.The circulatory system of the critically ill is often particularly susceptible to interference from respiration. Compensatory reserve is limited, ventilatory effort increased, and many critical care respiratory interventions place strain on the circulation, not seen in health.This review will examine the basic physiological mechanisms through which the pulmonary and circulatory systems interact. These mechanisms will then be applied to a variety of weaning, positive end-expiratory pressure (PEEP), and cardiopulmonary resuscitation techniques. It is hoped that this will provide the tools to understand clinical observations which would otherwise appear inexplicable.

show abstract

“…rate of at least 100 compressions per minutes. Some clinical trials and laboratory studies have shown that highfrequency CCs (120-150/min) improves hemodynamics compared to standard CCs, (8)(9)(10)(11) while other clinical and laboratory studies have found no effect of high-frequency CC and no improvement in hemodynamics over standard CPR. (12)(13)(14) Some authors have shown that even well trained paramedics tend to perform CCs faster than the appropriate frequency, (1) which may result in insufficient coronary perfusion.…”

Section: Discussionmentioning

confidence: 99%

Does the change of educational strategy for chest compression based on the change of guidelines affect on the quality of prehospital chest compression?

2012

View full text Add to dashboard Cite

show abstract

Hemodynamics in humans during conventional and experimental methods of cardiopulmonary resuscitation.

Abstract: High-fidelity hemodynamic recordings of aortic and right atrial pressures and the coronary perfusion gradient (the difference between aortic and atrial pressure) were

Cited by 126 publications

References 25 publications

Improved blood flow during prolonged cardiopulmonary resuscitation with 30% duty cycle in infant pigs.

Improved blood flow during prolonged cardiopulmonary resuscitation with 30% duty cycle in infant pigs.

Heart-lung interactions: applications in the critically ill

Does the change of educational strategy for chest compression based on the change of guidelines affect on the quality of prehospital chest compression?

Contact Info

Product

Resources

About