Hemofiltration and Peritoneal Dialysis in Infection-Associated Acute Renal Failure in Vietnam

Abstract

Hemofiltration is superior to peritoneal dialysis in the treatment of infection-associated acute renal failure.

Use of Peritoneal Dialysis in AKI

“…The mean age of patients ranged from 29.1 to 75.6 years. The causes of AKI were variable, with the most common causes being reported as sepsis (10,15,17,18,22,25,(27)(28)(29)(30)(33)(34)(35)(36)(37), prerenal causes or hypovolemia (6,17,22,26,28,30,32,(35)(36)(37), cardiac failure (10,18,22,30,35,36), postsurgery (10,18,19,26,31,35), and nephrotoxic agents (22,26,35,36). Mortality was reported at hospital discharge (6,15,23,35), at 30 days (10,17,18,27), or not specified.…”

“…The four RCTs scored 1 (India) (37), 1 (Nigeria) (34), 2 (Vietnam) (33), and 3 (Brazil) (10) points on the Jadad scale. In the Indian study comparing CRRT and PD (37), 5 of 55 randomized patients were excluded because of death within 6 hours of enrolment, of whom 1 patient was from the PD group.…”

“…Details of the PD technique were often not reported. Where data were available, the studies used either rigid catheters (19,26,28,33,35,37) or flexible Tenckhoff catheters (10,15,17,18,21,23,27,34). The automated cycler was used in four studies (10,17,18,23,26,27), and closed drainage systems were commonly used (10,15,17,18,22,23,26,27,37).…”

“…The automated cycler was used in four studies (10,17,18,23,26,27), and closed drainage systems were commonly used (10,15,17,18,22,23,26,27,37). As buffer, lactate (n=10 studies) (10,15,(17)(18)(19)22,23,(25)(26)(27), acetate (n=3) (24,33,37), and bicarbonate (n=1) were used (25). PD dose is discussed separately below.…”

“…EBP modalities included intermittent HD (n=7 studies) (29)(30)(31)(32)(34)(35)(36), daily HD (n=1 study) (10), and CRRT (n=4 studies) (15,33,36,37) (Table 4). Details of the vascular access, prescription, and dose were often not reported.…”