2024
DOI: 10.1096/fj.202302182r
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Hemolymph exosomes inhibit Spiroplasma eriocheiris infection by promoting Tetraspanin‐mediated hemocyte phagocytosis in crab

Yubo Ma,
Yu Yao,
Xiang Meng
et al.

Abstract: Exosomes released from infected cells are thought to play an important role in the dissemination of pathogens, as well as in host‐derived immune molecules during infection. As an intracellular pathogen, Spiroplasma eriocheiris is harmful to multiple crustaceans. However, the immune mechanism of exosomes during Spiroplasma infection has not been investigated. Here, we found exosomes derived from S. eriocheiris‐infected crabs could facilitate phagocytosis and apoptosis of hemocytes, resulting in increased crab s… Show more

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