Hemorragia digestiva de origen incierto por un adenocarcinoma endometrial metastásico. Respuesta al tratamiento hormonal

Pinto, Ana de Lorenzo; Salgado, Estela Fernández; Ortiz, Elena Castro; Arias, Ruth Baltar; Vazquez, S; Barro, Luis Ledo; Luis, J. Vázquez San; Astray, E. Vázquez

doi:10.1157/13111689

Cited by 4 publications

(4 citation statements)

References 16 publications

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“…Pinto et al used a scintigraphic study with 99mTc-marked RBCs to locate the site of GI bleed. 6 If EGD is not available and bleeding is brisk enough, CT angiography can be used to locate the source of bleeding. Tsai et al performed an EGD revealing a duodenal mass whereas endoscopic ultrasound revealed invasion of the muscularis propria.…”

Section: Discussionmentioning

confidence: 99%

Upper Gastrointestinal Bleeding due to Metastatic Endometrial Adenocarcinoma

et al. 2019

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Upper gastrointestinal bleeding (UGIB) is a life-threatening complication and a commonly encountered diagnosis requiring hospitalization. It is defined as bleeding proximal to the ligament of Treitz with the most common cause being peptic ulcer disease. There are multiple causes of UGIB and each of them presents its own unique diagnostic and management challenges. We present a rare case of UGIB due to endometrial adenocarcinoma metastatic to the third part of the duodenum. Most common sites of metastasis from endometrial adenocarcinoma are pelvic and paraaortic lymph nodes, and it is very rare for endometrial cancer to metastasize in gastrointestinal tract and then present as UGIB.

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Section: Discussionmentioning

confidence: 99%

Upper Gastrointestinal Bleeding due to Metastatic Endometrial Adenocarcinoma

et al. 2019

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“…Overall rate of endometrial cancer recurrence is approximately 15% [ 5 ]; in more than 50% of cases, it develops within 2 years, and about 75% occurs within 3 years after primary treatment [ 6 ]. Relapse of early stage EC is extremely rare; to our knowledge, in literature there are only three case reports of patients with single recurrent disease directly involving the digestive tract after a period of clinical latency: Wou et al [ 7 ] reported the occurrence of a gastrointestinal bleeding due to metastatic endometrial cancer 2 years after initial surgical treatment; Addison et al [ 8 ], respectively, described a single case of rectal metastasis from previously resected endometrial carcinoma and an appendiceal metastasis 10 years after primary 12 treatment [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Unusual Presentation of Recurrent Early Stage Endometrial Carcinoma 28 Years after Primary Surgery

Franchello

Fronda

Deiro

et al. 2015

Case Reports in Surgery

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Endometrial carcinoma is the most common neoplasia of female genital tract. The prognosis of early stage disease (FIGO I and FIGO II) is excellent: recurrence after surgery is less than 15%, most of which are reported within 3 years after primary treatment. Herein we report a case of late rectal recurrence from FIGO Ib endometrial adenocarcinoma. Patient had also familiar and personal history of colonic adenocarcinoma and previous findings of microsatellite instability (MSI); molecular analysis evidenced heterozygotic somatic mutation in MLH1 gene. Twenty-eight years after hysterectomy and bilateral salpingoovariectomy, a rectal wall mass was detected during routine colonoscopy. Patients underwent CT scan, pelvic MRI, and rectal EUS with FNA: histopathological and immunohistochemical analysis revealed differentiated carcinoma cells of endometrial origin. No neoadjuvant treatment was planned and low rectal anterior resection with protective colostomy was performed; histology confirmed rectal lesion as metastasis from endometrial carcinoma. Recurrence of early stage endometrial carcinoma after a long period from primary surgery is possible. It is important to keep in mind this possibility in order to set a correct diagnostic and therapeutic algorithm, including preoperative immunohistochemical staining, and to plan a prolonged follow-up program.

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“…Pinto et al . 40 reported a case of intermittent gastrointestinal bleeding in an elderly woman 2 years after treatment for endometrial cancer. CT not only showed the primary pelvic tumor, but also accurately showed intestinal invasion and lymph node metastasis.…”

Section: Diagnostic Value Of Eus In Pelvic Malignant Tumors With Colo...mentioning

confidence: 99%

Diagnostic value of endoscopic ultrasonography in pelvic masses with bowel involvement

She

Guo

2023

Therap Adv Gastroenterol

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Benign and malignant pelvic masses with or without intestinal invasion are common in women of childbearing age. Patients may have nonspecific symptoms and signs or experience no symptoms. Laparoscopic resection of pelvic masses is currently the mainstream treatment; therefore, accurate preoperative evaluation is not only essential for patients suspected of having intestinal invasion, but also extremely important for the selection of follow-up treatment. Procedures, including endoscopic ultrasonography (EUS), pelvic magnetic resonance imaging, abdominal computed tomography, vaginal ultrasonography, barium enema, and colonoscopy, aid in determining the presence, depth, and histology of the disease. In particular, the wide application and continuous developments in EUS techniques have improved the diagnostic accuracy for intestinal subepithelial and peripheral organ lesions. This article reviewed the clinical value of EUS in the diagnosis of benign and malignant pelvic masses with bowel involvement.

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Hemorragia digestiva de origen incierto por un adenocarcinoma endometrial metastásico. Respuesta al tratamiento hormonal

Cited by 4 publications

References 16 publications

Upper Gastrointestinal Bleeding due to Metastatic Endometrial Adenocarcinoma

Upper Gastrointestinal Bleeding due to Metastatic Endometrial Adenocarcinoma

Unusual Presentation of Recurrent Early Stage Endometrial Carcinoma 28 Years after Primary Surgery

Diagnostic value of endoscopic ultrasonography in pelvic masses with bowel involvement

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