1993
DOI: 10.1007/bf00571627
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Hemorrhagic radiation cystitis

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Cited by 7 publications
(5 citation statements)
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“…Irradiation of the bladder causes a progressive obliterative endarteritis of the small blood vessels, resulting in cellular hypoxia [52]. The rationale of hyperbaric oxygen treatment is to reverse the vascular radiation‐induced pathophysiology [53,54] by causing neovascularization of the bladder wall and so increase tissue oxygen tension. Since it was first described in the 1980s, more than 90 cases have been reported [55–61].…”
Section: Hyperbaric Oxygen Therapy For Haemorrhagic Radiation Cystitismentioning
confidence: 99%
“…Irradiation of the bladder causes a progressive obliterative endarteritis of the small blood vessels, resulting in cellular hypoxia [52]. The rationale of hyperbaric oxygen treatment is to reverse the vascular radiation‐induced pathophysiology [53,54] by causing neovascularization of the bladder wall and so increase tissue oxygen tension. Since it was first described in the 1980s, more than 90 cases have been reported [55–61].…”
Section: Hyperbaric Oxygen Therapy For Haemorrhagic Radiation Cystitismentioning
confidence: 99%
“…Although the present study showed promising clinical efficacy and safety of intravesical instillation treatment using KFL combined with thrombin and EGF for grade 2 ~ 4 radiation-induced HC, other treatment options should also be carefully considered according to individual patient condition. Hyperbaric oxygen (HBO) is thought to be the only treatment to reverse the vascular radiation-induced pathophysiology [ 19 ] and used for patients with severe end-stage hemorrhagic radiation cystitis in addition to cystectomy. Yuan Shao et al had discovered that intravesical instillation of hyaluronic acid (HA) was as effective in treating radiation-induced HC as HBO.…”
Section: Discussionmentioning
confidence: 99%
“…Die Hyperoxie induziert die primäre Neovaskularisierung und somit auch die Bildung von frischem Granulationsgewebe [7]. In der Literatur sind mehrere Berichte zur hyperbaren Sauerstofftherapie der radiogenen Zystitis zu finden [1, 5,10].…”
Section: Diskussionunclassified
“…Kontraindikationen der hyperbaren Sauerstofftherapie sind ausgeprägte chronisch-obstruktive Atemwegserkrankun-gen, Epilepsie, Glaukom, Katarakt, Klaustrophobie, Innenohrschwerhörigkeit sowie eine akut proliferierende maligne Erkrankung. Als Nebenwirkungen werden Sauerstoffintoxikation, Pneumothorax, Katarakt, fibrosierende Lungenveränderungen und Barotraumata beschrieben [10]. Die Silikose und das obstruktive Schlafapnoe-Syndrom bei dem hier behandelten Patienten erwiesen sich in Lungenfunktionsprüfungen in ihrer Ausprägung als von mittlerem Schweregrad, so dass sie keine Kontraindikation zur Durchführung der hyperbaren Sauerstofftherapie darstellten.…”
Section: Diskussionunclassified
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