Hemosiderotic dermatofibroma mimicking melanoma: A case report and review of the literature

Abstract

is a common benign skin tumor. Hemosiderotic dermatofibroma (HDF) is a rare variant of DF. It often mimics other skin lesions including melanocytic lesions and vascular tumors. In this report, we described the clinical features and histopathological findings of a rare HDF case that mimics melanoma. Dermatofibroma (DF) is a common benign cutaneous lesion generally reported in the trunk or extremities of young or middle-aged adults with a slight predominance in females. 1,2 Based on specific histopathological features, DF has multiple variants which may include but not limited to aneurysmal/hemosiderotic, 3 cellular, 4 epithelioid cell histiocytoma, 5 atypical (pseudosarcomatous), 6 atrophic, 7 and lipidized. 8 It usually presents as a solitary well-circumscribed nodule with reddish/ brown color on gross examination and central white patch and peripheral pigment network on dermatoscopy. 9 However, this disease has a wide range of presentations. About 29% DF cases harbor atypical macroscopic features resembling other skin malignancies including melanoma (16% of all cases), vascular tumor, and basal cell carcinoma. 10 Hemosiderotic DF (HDF) is a rare variant of DF which is known to have melanoma-like pattern. Skin examination by dermatoscopy is not able to reliably distinguish HDF from melanoma. 10,12 In this scenario, a definite diagnosis could only be made by histopathological examination. There are three cases of HDF reported in the literature from the United States. 13-15 Here, we report another case of HDF which was clinically suspicious for melanoma.

High-resolution permittivity estimation of ground penetrating radar data by migration with isolated hyperbolic diffractions and local focusing analyses

“…The isolation of diffractions and the migration had been proven effective in reducing the above-surface diffractions (Li et al, 2021a). Traditional methods perform migration to the whole data set without isolating each group of diffractions; thus, the cluttered diffractions are still strongly interfered in the migrated domain (Carpentier et al, 2010).…”

“…This method performs plane wave decomposition-based local curvature analysis to separate diffractions from reflections. However, as a data-driven method, it relies on curvature analysis in the data domain (Fomel et al, 2007;Li et al, 2021a;Song et al, 2021;Li and Zhang, 2022b) and is vulnerable to the influence of the original signal-to-noise ratio. Additionally, all rapid local variations of curvature tend to be regarded as diffractions, while the others are regarded as reflections.…”

A rare case of aneurysmal dermatofibroma with distinct dermatoscopic findings

“…3 In summary, aneurysmal dermatofibroma may show variable, ubiquitous dermatoscopic, and clinical features that may mimic more commonly observed, benign, or malignant cutaneous neoplasms. 5 Therefore, histopathologic examination has the uppermost significance for the determination of aneurysmal dermatofibroma from the other skin diseases.…”