Hemospermia and Expressed Tumor in the Urethra: An Unusual Presentation of Ductal Carcinoma of the Prostate

Rubinowicz, Diego; Soloway, Mark S.; Lief, Mathew; Civantos, Francisco

doi:10.1016/s0022-5347(05)67841-x

Cited by 17 publications

(6 citation statements)

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“…More recently, however, an association between prostate cancer and haematospermia has been established. 2,3 In a recent study looking at the incidence of prostate cancer in patients with haematospermia, Han et al 3 reported the diagnosis of prostate cancer in nearly 14% of men presenting with haematospermia.…”

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confidence: 99%

Haematospermia – A Systematic Review

Kumar

Kapoor

Nargund

2006

annals

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Haematospermia (or haemospermia) is a distressing symptom in sexually active men. In most cases, it is caused by non-specific inflammation of the prostate and seminal vesicles. In a small percentage of men, however, it may be a manifestation of genito-urinary or systemic malignancy, in particular prostate cancer. The purpose of this review is to explain the causes and management of patients with haematospermia.

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confidence: 99%

Haematospermia – A Systematic Review

Kumar

Kapoor

Nargund

2006

annals

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“…Evidence of association with malignancy is scarce and often limited to case reports or case series. Such cases have included primary seminal vesicle adenocarcinoma [ 14 ], metastatic melanoma to the seminal vesicle [ 15 ], primary testicular cancer [ 16 ], and primary prostate cancer [ 17 ]. One retrospective analysis of 26,126 men of ages 50 and older demonstrated 19 cases of cancer in the 139 men who presented with hematospermia (13.7% incidence) versus 6.5% of cancer cases seen in men without hematospermia [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Hematospermia and Cloacogenic Transitional Cell Carcinoma: A Twist on Significance and Meaning

Hennessey

Clément

Forouhar

et al. 2016

Case Reports in Urology

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A 52-year-old gentleman presented with recurrent hematospermia. Further history revealed recent onset of constipation and difficulty voiding. Rectal examination revealed a firm, polypoid mass and colonoscopy showed suspicious, ulcerated lesions of the rectal mucosa with narrowing of the rectal vault. Pathology demonstrated transitional cell carcinoma of the rectum. While transitional cell carcinoma is a common genitourinary cancer, its presence in the anus and rectum is exceedingly rare. Furthermore, hematospermia is generally not associated with malignancy. This case is a remarkable example of two pathologic processes presenting in rare form and underscores the value of a thorough investigation of hematospermia when associated with other clinical symptoms.

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“…21 Haemospermia has also been described due to tumour infiltration into the urethra. 22 These symptoms may also be seen in patients with acinar adenocarcinoma, but occur more frequently in DAC patients due to the periurethral location of the tumour. 23 Cystoscopic examination may show a villous or friable polypoid lesion protruding from the urethra, 9,12,21,[24][25][26][27] while digital rectal examination may be normal or reveal induration or a palpable nodularity.…”

Section: Clinical Featuresmentioning

confidence: 99%