2001
DOI: 10.1016/s0049-3848(00)00380-7
|View full text |Cite
|
Sign up to set email alerts
|

Hemostatic Activation in Acute Ischemic Stroke

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

4
49
2

Year Published

2006
2006
2021
2021

Publication Types

Select...
10

Relationship

1
9

Authors

Journals

citations
Cited by 53 publications
(55 citation statements)
references
References 29 publications
4
49
2
Order By: Relevance
“…*Denotes significant P value. [17][18][19] and elevated hemostatic markers were associated with an increased risk of recurrent stroke and stroke progression. 15,16 However, in univariate and multivariate analysis, we were unable to identify any group that did better with LMWH for any outcome measure.…”
Section: Discussionmentioning
confidence: 98%
“…*Denotes significant P value. [17][18][19] and elevated hemostatic markers were associated with an increased risk of recurrent stroke and stroke progression. 15,16 However, in univariate and multivariate analysis, we were unable to identify any group that did better with LMWH for any outcome measure.…”
Section: Discussionmentioning
confidence: 98%
“…Plasmin splits the fibrin into FDP and D-dimers when the coagulation and fibrinolytic system is activated. A number of studies have shown that D-dimer, C-reactive protein, and other markers of hemostatic activation associate with a stroke diagnosis 5,18,19,[21][22][23]28,31,35,39) and with progression and death in acute ischemic stroke 5,6,10,30,44) . The report by Laskowitz et al 22) suggests that a biomarker panel may add valuable and time-sensitive diagnostic information to early stroke evaluation and rapid identification of patients with suspected stroke, which would expand the availability of time-limited treatment strategies.…”
Section: Treatmentmentioning
confidence: 99%
“…We found that fibrin D -dimer, rather than fibrinogen or CRP, was the marker most strongly associated with progressing stroke [20]. In addition, there is a body of evidence from other studies suggesting that D -dimer is associated with poor outcome in acute stroke [18, 21, 22]. Although D -dimer is also an acute phase reactant, these observations raise the possibility that markers other than fibrinogen and CRP may be more strongly associated with poor outcome in acute stroke.…”
Section: Introductionmentioning
confidence: 99%