Hemostatic Agents Used to Stop Bleeding

Beaty, Rachel S.

doi:10.1007/978-3-319-30726-8_34

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Thrombin (Bovine Pooled Human Plasma Thrombin and Recombin1

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2021

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“…There are three forms of thrombin products differentiated based on type of plasma used to provide concentrated thrombin to rapidly convert fibrinogen to fibrin clot [61][62][63]. This class of biosurgicals should be used in cases of mild to moderate bleeding, mainly because such products tend to be easily washed off in the setting of brisk arterial bleeding or surgical irrigation [64].…”

Section: Thrombin (Bovine Pooled Human Plasma Thrombin and Recombinmentioning

confidence: 99%

Biosurgical Materials in Neurosurgical Applications: From Pioneers to Leaders

Petit-Me¹,

Stawicki²,

Firstenberg³

et al. 2021

Contemporary Applications of Biologic Hemostatic Agents Across Surgical Specialties [Working Title]

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Hemostasis in neurosurgery has evolved significantly over the past few decades. New advances in hemostatic agents, some developed specifically with neurosurgical applications in mind, allowed for more effective control of difficult intraoperative bleeding. These agents vary in the mechanism of action and each may be indicated in different and often highly specific situations. Here we present a review of the most commonly used hemostatic agents, their mechanism of action and their indications. Focus is placed on key aspects and considerations regarding the use biosurgical materials in neurosurgery, with emphasis on clinical appropriateness and patient safety.

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Section: Thrombin (Bovine Pooled Human Plasma Thrombin and Recombinmentioning

confidence: 99%