2023
DOI: 10.21203/rs.3.rs-3087417/v1
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Hemostatic capability of ultrafiltrated fresh frozen plasma compared to cryoprecipitate

Abstract: This in vitro study evaluated the potential hemostatic effect of fresh frozen plasma (FFP) ultrafiltration on clotting factors, coagulation parameters, and plasma properties. ABO-specific units of FFP (n = 40) were prepared for the concentrated FFP and cryoprecipitate. Plasma water was removed from FFP by ultrafiltration using a dialyzer with a pump running at a 300 ml/min. The aliquot of each concentrated FFP after 50, 100, 200, and 250 ml of fluid removal were served for the standard coagulation assay, measu… Show more

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