Hemostatic Techniques Reduce Hospital Stay Following Multilevel Posterior Cervical Spine Surgery

Cho, Samuel K.; Yi, Jin-Seok; Park, Moon Soo; Hu, Guangxun; Zebala, Lukas P.; Pahys, Joshua M.; Kang, Matthew M.; Lee, Dong‐Ho; Riew, K. Daniel

doi:10.2106/jbjs.k.00632

Cited by 28 publications

(17 citation statements)

References 17 publications

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“…For this purpose, we administrated histamine topically using gelfoam on the lesion site after surgery. Gelfoam is an absorbable medical device used as a hemostatic and as a carrier to deliver some agents such as thrombin in the clinic . Topical treatment of gelfoam soaked with histamine makes it more convenient for administration.…”

Section: Discussionmentioning

confidence: 99%

Histamine Promotes Locomotion Recovery After Spinal Cord Hemisection via Inhibiting Astrocytic Scar Formation

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Histamine Promotes Locomotion Recovery After Spinal Cord Hemisection via Inhibiting Astrocytic Scar Formation

et al. 2015

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“…1,2,26,27 The efficacy of drains has been challenged for many surgical procedures; however, no study has assessed the necessity of drain use after ACDF. 3–18,22–25 The current study was designed to identify factors that affect drain output after ACDF in order to assist surgeons with the decision of whether or not to place a drain postoperatively.…”

Section: Discussionmentioning

confidence: 99%

Factors Predictive of Increased Surgical Drain Output After Anterior Cervical Discectomy and Fusion

Basques

Bohl

Golinvaux

et al. 2014

Spine

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Study Design Retrospective cohort study. Objective To identify factors that are independently associated with increased surgical drain output in patients who have undergone ACDF. Summary of Background Data Surgical drains are typically placed following ACDF to reduce the risk of complications associated with neck hematoma. The orthopaedic literature has repeatedly challenged the use of surgical drains following many procedures, and there are currently no guidelines for determining which patients are most likely to benefit from drain placement after ACDF. Methods Consecutive patients who underwent elective ACDF with surgical drain placement at a single academic institution between January 2011 and February 2013 were identified using billing records. Patient information was abstracted from the medical record. Patients were categorized based on normal or increased total drain output, with increased drain output defined as total drain output ≥ 50th percentile (30mL). A multivariate logistic regression was used to determine which factors were independently associated with increased drain output. Results A total of 151 ACDF patients met inclusion criteria. Total drain output ranged from 0 mL to 265 mL. The average drain output for this cohort was 42.3 ± 45.5 mL (mean ± standard deviation). Among all patients in the study, 80 patients had increased drain output (drain output ≥ 50th percentile or 30 mL). Multivariate analysis identified three independent predictors of increased drain output: age ≥ 50 years (Odds Ratio [OR] = 3.9), number of levels (2 levels, OR = 2.7; 3–4 levels, OR = 17.0), and history of smoking (OR = 2.8). One patient developed a postoperative neck hematoma while a drain was in place. Conclusion Patients with the above-identified factors associated with increased drain output may benefit most from surgical drain placement after ACDF. Nonetheless, neck hematoma is still possible even with drain use.

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“…Vestergaard et al (2010) indicated that the use of Ostene instead of bone wax could contribute to a reduction in the incidence of sternal dehiscence and chronic inflammation. Cho et al (2012) suggested the application of a thrombinsoaked, absorbable gelatin compressed sponge at the end of multilevel posterior cervical spinal surgery significantly decreased post-operative drain output.…”

Section: Introductionmentioning

confidence: 99%

Biodegradable composite scaffolds of bioactive glass/chitosan/carboxymethyl cellulose for hemostatic and bone regeneration

Chen

Pan

et al. 2014

Biotechnol Lett

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Hemostasis in orthopedic osteotomy or bone cutting requires different methods and materials. The bleeding of bone marrow can be mostly stopped by bone wax. However, the wax cannot be absorbed, which leads to artificial prosthesis loosening, foreign matter reaction, and infection. Here, a bioactive glass/chitosan/carboxymethyl cellulose (BG/CS/CMC) composite scaffold was designed to replace traditional wax. WST-1 assay indicated the BG/CS/CMC composite resulted in excellent biocompatibility with no cytotoxicity. In vivo osteogenesis assessment revealed that the BG/CS/CMC composite played a dominant role in bone regeneration and hemostasis. The BG/CS/CMC composite had the same hemostasis effect as bone wax; in addition its biodegradation also led to the functional reconstruction of bone defects. Thus, BG/CS/CMC scaffolds can serve as a potential material for bone repair and hemostasis in critical-sized bone defects.

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Hemostatic Techniques Reduce Hospital Stay Following Multilevel Posterior Cervical Spine Surgery

Abstract: Therapeutic Level III.

Cited by 28 publications

References 17 publications

Histamine Promotes Locomotion Recovery After Spinal Cord Hemisection via Inhibiting Astrocytic Scar Formation

Histamine Promotes Locomotion Recovery After Spinal Cord Hemisection via Inhibiting Astrocytic Scar Formation

Factors Predictive of Increased Surgical Drain Output After Anterior Cervical Discectomy and Fusion

Biodegradable composite scaffolds of bioactive glass/chitosan/carboxymethyl cellulose for hemostatic and bone regeneration

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