This study aims to investigate the role of mindfulness and various demographic variables in explaining the resilience of university students. The research was carried out within the framework of a relational screening model based on a quantitative research approach. The sample of the study consisted of 392 students who were seleceted by suitable sample strategy from three programs (psychological counselling and guidance, social work and nursing) of a public university. As data collection tools, Mindfulness Scale, Resiliency Attitude and Skill Scale and Personal Information Form were used. Multiple regression analysis was used in the analysis of the obtained data. As a result of the research, it was understood that mindfulness and elevation of the class level explained the resilience in a meaningful and positive way. However, it was determined that the decrease in the population of the place of residence before coming to university explained the resilience of individuals in a meaningful and negative way. On the other hand, it was found that the variables of gender, program in education, general academic grade point average, receiving psychological support, and educational status related to resilience, place of residence in university life, and perceived income level did not significantly explain resilience.