Henri Meige (1866–1940)

Owecki, Michał K.; Bogusz, Halina; Magowska, Anita

doi:10.1007/s00415-017-8575-z

Cited by 3 publications

(1 citation statement)

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“…Meige syndrome (MS) is a form of segmental craniocervical dystonia characterized by the co-occurrence of blepharospasm (involuntary eye blinking) and oromandibular dystonia (involuntary movements affecting the lower face and jaw) [ 1 ]. Henry Meige, a pioneering French neurologist in the early 20th century, meticulously documented this amalgamation of symptoms, thereby establishing its recognition within neurological practice [ 2 ]. Symptoms typically initiate with the involvement of the orbicularis oculi muscles, ranging from heightened blinking to eventual eye closure difficulties.…”

Section: Introductionmentioning

confidence: 99%

A Presentation of Meige Syndrome With Associated Upper Motor Neuron Symptoms

Valencia Uribe,

Hossain,

Rizvi

et al. 2024

Cureus

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Meige syndrome (MS) is a cranial dystonia that involves blepharospasm and oromandibular dystonia. It can also evolve to include other adjacent muscle groups in the cervical region. It typically presents in middleaged females, and while the disorder is relatively uncommon, its exact prevalence varies. Diagnosis is typically made with a thorough history and physical and workup to rule out other causes. Treatment options include medical management with gamma-aminobutyric acid (GABA) antagonists, dopamine antagonists, and anticholinergics for short-term management. Long-term treatment options are Botox and deep brain stimulation. This case report presents a 56-year-old female with a complex presentation of MS; the patient's symptoms progressed from isolated blepharospasms to involve orofacial and cervical musculature. A distinctive aspect of this case was the simultaneous presence of upper motor neuron (UMN) signs in the patient alongside acute to subacute compression fractures of the superior endplate of C7 and T3, as revealed by cervical spine imaging. Treatment with clonazepam led to significant symptomatic improvement, highlighting the importance of a multimodal approach in managing MS. This case underscores the need for careful clinical evaluation, collaboration with movement disorder specialists, and ongoing research efforts to enhance understanding and treatment of MS.

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Section: Introductionmentioning

confidence: 99%