2006
DOI: 10.1051/ject/200638307
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Heparin Sensitivity Test for Patients Requiring Cardiopulmonary Bypass

Abstract: Anticoagulation for the open heart surgery patient undergoing cardiopulmonary bypass (CPB) is achieved with the use of heparin. The industry standard of activated clotting time (ACT) was used to measure the effect of heparin. The commonly acceptable target time of anticoagulation adequacy is 480 seconds or greater. Some patients, however, exhibit resistance to standard dosing of heparin and do not reach target anticoagulation time (480 seconds). Antithrombin III deficiency has been previously cited as the caus… Show more

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Cited by 8 publications
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