Hepatic alveolar hydatidosis — A malignant masquerade

Vijay, Kapileshwer; Vijayvergia, Varunika; Saha, Anupam; Naidu, C. S.; Rao, Pankaj P.; Godara, Rajesh

doi:10.1007/s13126-013-0026-4

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…India is in the northern hemisphere and borders several endemic regions of E. multilocularis. CE is endemic in several regions in India, such as Andhra Pradesh, Chennai, and Kashmir; however, AE is not endemic in India [11], and only a few isolated cases have been reported in the past [12][13][14][15]. There has been a rising trend of AE in Kashmir, India, recently [16,17].…”

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confidence: 99%

A Case Series and Literature Review of Alveolar Echinococcosis in Kashmir, India: An Emerging Endemic Zone for Echinococcus multilocularis

Khuroo,

Rather

2024

Life

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A prospective study on 110 patients with echinococcosis at Dr. Khuroo’s Medical Clinic, Srinagar, Kashmir, India, from March 2019 to April 2024 identified 12 cases (4 males, 8 females; mean age of 46.58 ± 11.97 years) of Alveolar echinococcosis (AE). Two patients were detected through ultrasound examinations carried out for unrelated causes; one presented with features of liver abscess, and nine had pain in the right upper quadrant for a mean period of 2.2 ± 1.79 years. All had the liver as the primary organ involved, with 15 tumor masses of a mean maximum diameter of 9.22 ± 3.21 cm and volume of 426 ± 374.61 cm3. Tumors placed centrally had invaded vessels and the biliary tract in eight patients, and those placed peripherally had invaded the liver capsule and adjacent organs in nine patients. Histologic examination of liver biopsies or resected organs revealed necrotic lesions, calcifications, and granulomatous inflammation with slender, thin-walled vesicles of bizarre configuration that stained strongly eosinophilic with periodic acid Schiff. Two patients had segmental liver resections; one was treated with liver aspiration, while the other nine with advanced disease received chemotherapy with albendazole along with praziquantel. Patients showed clinical improvement on a median follow-up of 12 months (range 1 to 60 months); however, MRI T2-weighted images and 18F-FDG-PET-CECT scans in two patients showed active disease on follow-up at one and five years, respectively. A systematic review detected 146 cases of AE in India from 1980 to April 2024. Twenty cases were from foreign countries, mostly from Central Asian republics, and 118 (93.65%) of the remaining 126 Indian patients were permanent residents of Kashmir Valley. The disease affected a population of 79,197 residing in 22 villages from 5 border districts of the valley. These villages were either high in or adjacent to the Himalayan mountain range. Disease prevalence in the affected population was 146.47/105 (males 131.53/105 and females 163.18/105) and the incidence was 12.41/105/year (males 11.16/105/year and females 13.81/105/year). Possible causes of the emergence of AE are discussed, and future directions for research to face this challenge arebeen identified.

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Section: Introductionmentioning

confidence: 99%

A Case Series and Literature Review of Alveolar Echinococcosis in Kashmir, India: An Emerging Endemic Zone for Echinococcus multilocularis

Khuroo,

Rather

2024

Life

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“…Man gets infected accidentally and eggs develop into the metacestode stage in the liver, proliferate asexually, infiltrate to the peripheral parts of the liver and metastasize to other organs, hence this potentially fatal disease is also known as malignant hydatid disease. 3 A rare case of alveolar hydatid disease of liver is being reported. We describe the clinical, radiological and pathological features to highlight the diagnostic difficulty encountered, and successful management of the case.…”

Section: Introductionmentioning

confidence: 99%

Alveolar hydatid disease of the liver: A rare entity in India

Bhatia

Ravikumar

Naidu

et al. 2016

Medical Journal Armed Forces India

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Prevalence of Hepatic Alveolar hydatid in a Nonendemic Region of North India in Hospital-based Population

Ahmad

Ilyas

Ashraf

et al. 2021

Journal of Datta Meghe Institute of Medical Sciences University

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Objective: The objective of this study was to calculate the prevalence of hepatic alveolar hydatid disease in hospital-based population in North India, a nonendemic region for alveolar hydatid disease. Materials and Methods: This study was conducted at a tertiary care center in North India between April 2017 and March 2019. Patients with suspected hepatic alveolar hydatid on ultrasonography were evaluated with further imaging studies based on classical radiological findings and then confirmed by histopathology. Results: Twenty-five cases of hepatic alveolar hydatid were diagnosed primarily based on the classical imaging/radiological findings with histopathology confirmation, with a 2-year period prevalence of 0.207 cases/1000 population. Majority of the cases were in the age group of 41–60 years, with a mean age of 53.04 years. Fifty-two percent of the cases were female. Majority of them were from hilly areas and working with livestock animals. Abdominal pain was the most common presenting symptom. Conclusion: Hepatic alveolar hydatid is considered as a rare disease in India; however, the increased number of cases been diagnosed in our study could be either due to increased diagnostic modalities or due to actual increase in the number of cases. Therefore, hepatic alveolar hydatid should be considered in the differentials of suspicious liver mass in nonendemic regions.

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Hepatic alveolar hydatidosis — A malignant masquerade

Cited by 3 publications

References 8 publications

A Case Series and Literature Review of Alveolar Echinococcosis in Kashmir, India: An Emerging Endemic Zone for Echinococcus multilocularis

A Case Series and Literature Review of Alveolar Echinococcosis in Kashmir, India: An Emerging Endemic Zone for Echinococcus multilocularis

Alveolar hydatid disease of the liver: A rare entity in India

Prevalence of Hepatic Alveolar hydatid in a Nonendemic Region of North India in Hospital-based Population

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