Hepatic artery embolisation; successful treatment of multinodular haemangiomatosis of the liver

Vomberg, P. P.; Büller, H. R.; Marsman, J. W. P.; Lam, Jan; Zaane, D. J. Van; Heymans, H. S. A.

doi:10.1007/bf00441741

Cited by 8 publications

(1 citation statement)

References 15 publications

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“…Hemangiomas affecting the liver are rare in children and they may present considerable problems of diagnosis and treatment. Spontaneous regression may occur, but an overall mortality of 70% has been reported due to associated congestive heart failure and hemorrhage [11]. The cardiac failure results from massive arteriovenous shunting in the lesions in the liver.…”

Section: Presentationmentioning

confidence: 99%

Hepatic hemangiomas

Hobbs

1990

World j. surg.

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There are 2 main and different forms of hepatic hemangiomas--those of early childhood and those of later adult life. The former, called infantile hepatic hemangioendothelioma, may be life-threatening due to arteriovenous shunting in extensive lesions resulting in cardiac failure. Although they may resolve spontaneously, if cardiac failure develops, they must be treated aggressively by arterial ligation or embolization. The adult form rarely gives rise to symptoms and should be left alone. Spontaneous rupture is extremely rare but may follow needle biopsy and it is in this group of patients that the occasional death has been reported. Biopsy should, therefore, be avoided. Symptomatic lesions should be resected in a specialized center where the morbidity and mortality of liver resection is acceptably very low.

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Section: Presentationmentioning

confidence: 99%

Hepatic hemangiomas

Hobbs

1990

World j. surg.

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Treatment of Kasabach-Merritt syndrome by embolisation of a giant liver hemangioma

et al. 2001

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We report the case of a 14-month-old child with Kasabach-Merritt Syndrome, due to a giant liver hemangioma. The therapeutic approach consisted of peripheral transcatheter embolisation of the right hepatic artery with Ivalon microspheres without the addition of thrombogenic material. This procedure brought to a sensible permanent reduction of the size of the liver hemangioma with normalisation of the previous altered coagulation parameters after 6 years of follow-up.

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Infantile hepatic hemangiomas. Clinical features, radiologic investigations, and treatment of 20 patients

Stanley

Geer

Miller

et al. 1989

Cancer

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The clinical features, radiologic investigation, and treatment of 20 infants with hepatic hemangiomas are presented. Palpable abdominal mass (n = 18) and cardiac failure (n = 11) were the common presenting features. Nine patients had hyperconsumptive coagulopathy. Seven patients had other hemangiomas. Ultrasound (n = 15) showed the number and distribution of the hemangiomas within the liver. Hypoechoic and hyperechoic elements were present in addition to prominent vascular channels and diminished caliber of the distal aorta. Radionuclide sulfur colloid (n = 12) and labeled red blood cell (n = 7) studies showed the distribution and vascularity of the hemangiomas. Computed tomography (n = 8) revealed central hypointensity with marked peripheral enhancement after contrast. Arteriography now performed only as a prelude to therapeutic embolization demonstrated hypervascularity in each patient, contrast pooling in six and early draining veins in five. Magnetic resonance scanning (n = 3) showed decreased signal intensity on T1 images and high intensity signal on T2. In two patients, there was resolution or improvement of the hemangiomas without therapy. Four patients had surgery (lobectomy [2], trisegmentectomy [1], and surgical evacuation of a central hematoma [1]). Steroids and radiation were given to seven patients, and one patient also required therapeutic embolization. Steroids were the initial therapy in five patients, one of whom later required therapeutic embolization and another cyclophosphamide. Two patients were treated initially with radiation therapy, one of whom also needed emergency hepatic artery ligation. Seventeen of the 20 patients are alive and well from 6 months to 14 years after diagnosis.

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Hepatic artery embolisation; successful treatment of multinodular haemangiomatosis of the liver

Abstract: A patient with multinodular haemangiomatosis of the liver, rapidly deteriorating in the first weeks of life due to severe progressive congestive heart failure, was successfully treated by hepatic artery catheter embolisation at the age of 6 weeks.

Cited by 8 publications

References 15 publications

Hepatic hemangiomas

Hepatic hemangiomas

Treatment of Kasabach-Merritt syndrome by embolisation of a giant liver hemangioma

Infantile hepatic hemangiomas. Clinical features, radiologic investigations, and treatment of 20 patients

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