2009
DOI: 10.1080/17471060802449353
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Hepatic dysfunction after shock: Clinical parameters and biological pathways for therapeutic intervention

Abstract: The prevalence of hepatic dysfunction was thought to be : 1% in intensive care unit (ICU) patients, but is now being recognized to be 10%. Mortality and length of ICU stay are directly affected by hepatic dysfunction, raising the need for a better understanding of this disorder in order to develop therapeutic options that go beyond the current practice of supportive care. The etiologies of hypoxic hepatitis are discussed, together with their differentiating physiological parameters. The liver's compensatory me… Show more

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