Hepatic expression of interleukin 8 in diagnosing biliary atresia

Abstract

and vegetables, and whole grains. As we mentioned, both HEI-2010 and aMED have been associated with a variety of disease outcomes.1 Nevertheless, it is also important to examine distinct aspects of diet as well, which is why we included these data.As there may be some confusion about the terms used for each dietary component in our article, we wish to clarify here. The total protein foods component in HEI-2010 specifically refers to lean red meat and poultry, eggs, as well as beans and peas (which are included when the total protein foods standard is not met). It does not include dairy; or seafood and plant proteins (except beans and peas), which are separate components in HEI-2010. We would also like to clarify that the red and processed meat of aMED was actually associated with CLD and HCC in the opposite direction, as mentioned by Vinciguerra, with participants eating more red and processed meat having nonsignificantly higher risk of HCC incidence and CLD mortality than participants eating less. Looking across the sources of protein, we see some evidence for increased risks, with eating more red and processed meat and decreased relative risks with eating more eggs, beans, and peas. Associations for dairy were mixed for each endpoint.As is always the case, and particularly with regard to observational studies, public health recommendations should only be made based on the totality of the evidence, not on the results of individual studies. Unfortunately, relatively few studies of diet in CLD and HCC are available. Future studies of dietary patterns and individual dietary components, such as protein, are needed.

Interleukin‐8: A critical chemokine in biliary atresia

“…IL‐8 is expressed and secreted at high levels both in vitro and in vivo in human BA, and recent studies suggest that it is critical for BA inflammation and progression . Using oligonucleotide‐based gene chips and confirming their results by reverse transcriptase polymerase chain reaction, Bezerra et al .…”