Hepatic laceration and total parenteral nutrition extravasation due to dislocation of an umbilical venous catheter

Baldo, Francesco; Pirrone, Angela; Trappan, Antonella

doi:10.1111/jpc.15779

Cited by 1 publication

(2 citation statements)

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“…Yet, this procedure is not without risk, and severe complications may occur when the UVC is misplaced, such as thromboembolism, vascular injury, infection, and sepsis. In rare situations, misplacement can cause intraperitoneal extravasation of TPN followed by hepatic injury 1–9 . We report a unique instance of severe liver injury caused by TPN extravasation from a UVC and review the relevant literature.…”

Section: Introductionmentioning

confidence: 98%

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Hepatic extravasation of total parenteral nutrition following umbilical venous catheter insertion: A rare complication

Berger,

Gavri,

Jesin

et al. 2023

JPGN rep.

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Umbilical venous catheters are commonly inserted in critically ill newborns and can lead to severe complications when misplaced. We report a preterm female with a prenatal diagnosis of duodenal atresia who presented 2 days after the surgical repair with abdominal distension, hemodynamic instability, elevated liver enzymes with severe cholestatic jaundice, and a hepatic collection on abdominal sonography. An urgent explorative laparotomy demonstrated a large amount of white, milky‐appearing fluid in the abdominal cavity. Together with the sonographic findings, this led to the diagnosis of hepatic total parenteral nutrition extravasation. Upon removal of the umbilical venous catheter line, the infant's clinical state rapidly improved; however, cholestasis continued for months, with a very slow resolution. During follow‐up, the liver enzymes normalized, and a complete resolution of the liver collection was observed, without drainage.

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Section: Introductionmentioning

confidence: 98%

“…In rare situations, misplacement can cause intraperitoneal extravasation of TPN followed by hepatic injury. 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 We report a unique instance of severe liver injury caused by TPN extravasation from a UVC and review the relevant literature.…”

Section: Introductionmentioning

confidence: 99%