2021
DOI: 10.1038/s41565-020-00836-6
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Hepatic macrophages act as a central hub for relaxin-mediated alleviation of liver fibrosis

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Cited by 93 publications
(75 citation statements)
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“…CCL2, C-C motif chemokine ligand 2; CCR2, C-C chemokine receptor type 2; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand. New findings from Hu et al 1 are highlighted in red. Figure adapted with permission from ref.…”
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confidence: 95%
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“…CCL2, C-C motif chemokine ligand 2; CCR2, C-C chemokine receptor type 2; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand. New findings from Hu et al 1 are highlighted in red. Figure adapted with permission from ref.…”
mentioning
confidence: 95%
“…Whilst the potential for RLX to modulate macrophage phenotype in the context of fibrosis has been described previously 10 , the identification of Nur77 as a key transcriptional driver of pro-resolution macrophage properties and the demonstration that restorative macrophages promote the deactivation of activated HSC via the release of exosomes containing microRNA miR-30a-5p, provide important new insights for the field (Fig. 1) 1 .…”
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confidence: 95%
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