Hepatic Perfusion Changes in Patients with Cirrhosis

Koranda, Pavel; Mysliveček, M; Erban, J; Seidlová, V; Husak, V.

doi:10.1097/00003072-199907000-00007

Cited by 14 publications

(9 citation statements)

References 5 publications

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“…It is known that there are substantial changes in certain perfusion parameters in patients with cirrhosis ( 25,26,(38)(39)(40). Miles et al (30) and Blomley et al (31) have shown an increase in arterial perfusion and a decrease in portal venous perfusion with the slope method.…”

Section: Discussionmentioning

confidence: 99%

Liver Fibrosis in Chronic Hepatitis C Virus Infection: Differentiating Minimal from Intermediate Fibrosis with Perfusion CT

Ronot¹,

Asselah²,

Paradis³

et al. 2010

Radiology

118

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The results of this study show that perfusion changes occur early during fibrosis in chronic HCV infection and can be detected with perfusion CT. Perfusion CT may help to discriminate minimal from intermediate fibrosis. Mean transit time appears to be the most promising perfusion parameter for differentiating between fibrosis stages, although the large amount of overlap in the measured parameters limits the clinical utility of this test at present.

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Section: Discussionmentioning

confidence: 99%

Liver Fibrosis in Chronic Hepatitis C Virus Infection: Differentiating Minimal from Intermediate Fibrosis with Perfusion CT

Ronot¹,

Asselah²,

Paradis³

et al. 2010

Radiology

118

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“…The results of other authors 20 are also in accordance. Koranda et al 21 using HPI, confirmed that the net hepatic arterial blood flow is also increased in patients with cirrhosis. Fanfani et al 22 proved that HPI was reduced only in cirrhotic patients but not in those with chronic hepatitis, which is only partly in accordance to our findings.…”

Section: Discussionmentioning

confidence: 88%

Estimation of the relative liver perfusion using two methods of radionuclide angiography in the patients with hemodynamic disorders in the portal system

Artiko¹,

Šobić-Šaranović²,

Pavlović³

et al. 2008

ACTA CHIR IUG

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The aim of this study is the assessment of the relative arterial and venous contribution to the total liver blood flow (hepatic perfusion index-HPI), with two methods (S1 and S2), and estimation of their value. With this correction, HPI nonsignificantly increases (p>0.05) in all the groups of patients, with a very high correlation between the HPI (S1) and HPI (S2) values (p<0.01). In comparison to the portal perfusion in controls, values were significantly (p<0.01) lower in chronic active hepatitis and liver cirrhosis and differed between themselves (p<0.01). In the groups of cirrhotic patients with esophageal varices, sclerosated esophageal varices, recanalized umbilical vein, portal thrombosis and cavernous portal vein, portal perfusion was lower (p<0.01) than in controls, chronic active hepatitis and liver cirrhosis without collaterals. Both angioscintigraphic methods are useful for the estimation of the disturbances in the portal system. Because of the more exact estimation of the liver perfusion, S2 is recommended.

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“…As liver fibrosis becomes more severe, the effective sinusoidal perfusion is further reduced, and portal hypertension progresses, even leading to intrahepatic portal vein reflux 10 . In response to the compensatory increase in the hepatic arterial blood flow, 11 under normal conditions, the proportion of blood supplied by the hepatic artery and the portal vein is gradually reversed. Consequently, the hepatic artery becomes the primary effective blood source for the liver.…”

Section: Discussionmentioning

confidence: 99%

Contrast‐Enhanced Sonography for Quantitative Assessment of Portal Hypertension in Patients With Liver Cirrhosis

Zhang

et al. 2014

J of Ultrasound Medicine

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Hepatic Perfusion Changes in Patients with Cirrhosis

Abstract: The results confirm that the net hepatic arterial blood flow is increased in patients with cirrhosis. Radionuclide angiography accompanied by calculation of arterial perfusion indices may provide semiquantitative parameters of net hepatic arterial blood flow.

Cited by 14 publications

References 5 publications

Liver Fibrosis in Chronic Hepatitis C Virus Infection: Differentiating Minimal from Intermediate Fibrosis with Perfusion CT

Liver Fibrosis in Chronic Hepatitis C Virus Infection: Differentiating Minimal from Intermediate Fibrosis with Perfusion CT

Estimation of the relative liver perfusion using two methods of radionuclide angiography in the patients with hemodynamic disorders in the portal system

Contrast‐Enhanced Sonography for Quantitative Assessment of Portal Hypertension in Patients With Liver Cirrhosis

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