Hepatic perivascular epithelioid cell tumor

Abstract

Rational:Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal neoplasm which expresses both myogenic and melanocytic markers. PEComas are found in a variety locations in the body, but up to now only approximately 30 cases about hepatic perivascular epithelioid cell tumor are reported in English language worldwide.Patient concerns:A 32-year-old woman was admitted in our hospital with intermittent right upper quadrant pain for 1 month and recent (1 day) progressive deterioration.Diagnoses:Based on the results of the laboratory examinations and the findings of the computed tomography, the diagnosis of hepatic hamartoma or the hepatocecullar carcinoma with hemorrhage was made.Interventions:The patient underwent a segmentectomy of the liver, and the finally diagnosis of hepatic PEComa was made with immunohistochemical confirmation with HMB-45 and SMA.Outcomes:There is no clinical or radiographic evidence of recurrence 9 months after surgery.Lessons:This kind of tumor is extremely rare and the natural history of PEComa is uncertain, as the treatment protocol for hepatic PEComa has not reached a consensus. But the main treatment of the disease may be surgical resection. Only after long term follow-up can we know whether the tumor is benign or malignant. It appears that longer clinical follow-up is necessary in all patients with hepatic PEComas.

Liver perivascular epithelioid cell tumor in a patient with systemic lupus erythematosus

“…Hepatic pecomas are rare but increasingly recognized tumors. To date approximately 33 cases of hepatic pecomas have been reported [ [1] , [2] , [3] ].They can occur at any age, although it has been reported that they predominantly affect women aged 30–50 years old [ 11 ]. Hepatic PECOMA may occur as a solitary mass or as multiple lesions, which have been suggested to be associated with tuberous sclerosis.…”

“…Patients are often asymptomatic. Gastrointestinal symptoms exist when the tumor size cause localized pressure effect [ 1 ]. Imaging diagnosis can be challenging because the quantity of adipose tissue, irregular vessels and smooth muscle cells is various.…”

“…Perivascular epithelioid cell tumor (PECOMA) is a rare mesenchymal neoplasm which expresses both myogenic and melanocytic markers [ [1] , [2] , [3] ]. PECOMA can arrive from many locations of the body such as kidney, pancreas, urinary bladder, uterus and liver.…”

Pyogenic liver abscess: treatment modalities

“…Conclusion: IHS mimics HCC on imaging and should be considered as a differential diagnosis when a history of splenic trauma or splenectomy is present.Additionally,risk factors for HCC warrant consideration,and if absent,IHS should be considered as a differential.Laparoscopic liver resection can be performed with minimal morbidity and enables definitive diagnosis with histopathological examination and avoids the need for long term surveillance. 1 , H. Mestiri 1 and T. Khalfallah 1 1 Mongi Slim La Marsa, Visceral surgery, and 2 Mongi Slim La Marsa, Gastroenterology, Tunis, Tunisia Background: Treatment of pyogenic liver abscesses (PLA) is not well codified yet. Our aim is to compare treatment modalities of PLA that are antibiotics, percutaneous drainage and surgical drainage.…”

Liver pecoma: perivascular epithelioid tumor. a case report

“…Results: Liver PEComas were before considered as benign tumors, with surgical treatment in selected cases. The publications in the medical literature of some cases that confirm a malign transformation of AML have made the surgical indications for this pathology a controversial issue, recommending it in exophytic, >5cm or fast growing tumors [1][2] [3]. Conclusion: Nowadays, liver PEComas are considerate as rare tumors with risk of malignancy in some cases, making the surgical intervention the primary treatment.…”