Hepatic Radiofrequency Ablation

Iannitti, David A.; Dupuy, Damian E.; Mayo-Smith, William W.; Murphy, Brian L.

doi:10.1001/archsurg.137.4.422

Cited by 141 publications

(88 citation statements)

References 51 publications

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“…However, even using a more aggressive approach, the efficacy of RFA has been proven to be limited by tumor size [36]. Lesions measuring >5 cm have at best only a 50% chance of being completely ablated [40]. Therefore, most authors do not recommend the use of RFA for tumors >5-6 cm because of the technical limitations of the current equipment used and their inability to provide complete coagulative necrosis [7].…”

Section: The Use Of Rfa In Nonsurgical Candidatesmentioning

confidence: 99%

RFA for Liver Tumors: Does It Really Work?

Higgins

Berger

2006

The Oncologist

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The use of radiofrequency ablation (RFA) is increasing in the treatment of both primary and metastatic hepatic tumors. However, the role of RFA has yet to be clearly defined in patients who are still considered amenable to surgical intervention. Future prospective studies are needed to define whether RFA can be used as an alternative to surgery in certain patient populations. In the interim, radiofrequency ablation technology will continue to advance and serve as both a palliative and potentially curative intervention for individuals with hepatic tumors. The Oncologist 2006;11:801-808

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Section: The Use Of Rfa In Nonsurgical Candidatesmentioning

confidence: 99%

RFA for Liver Tumors: Does It Really Work?

Higgins

Berger

2006

The Oncologist

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“…Using RFA, treatment response has been found to correlate best with the size of the lesion; a complete response rate between 80%-90% in tumors up to 3 cm in diameter [24][25][26][27] , and 50%-70% in lesions between 3 and 5 cm in diameter [25,[28][29][30][31] . Five-year survival rates following RFA were reported as 48%-71% by some studies [32][33][34] .…”

Section: Rfamentioning

confidence: 99%

Ablative techniques in hepatocellular carcinoma treatment

Naeem¹,

Abid²

2018

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Hepatocellular carcinoma has been known to arise commonly in the setting of chronic liver disease. Due to its association with cirrhosis, patients with hepatocellular carcinoma often present with markedly diminished hepatic functional reserve, making them poor surgical candidates. For such patients, image-guided percutaneous ablative modalities have provided a viable alternate curative therapy. Although treatment allocation is a decision based on a number of factors, patients eligible for percutaneous ablation generally include those with early stage disease, hepatocellular carcinoma with disease limited to the liver and no extra-hepatic metastases. While percutaneous ethanol injection is the seminal technique, newer developments have led to it being replaced by percutaneous radiofrequency ablation as the most commonly employed procedure, due to a better efficacy as well as safety profile. Other ablative modalities including microwave ablation, laser ablation and cryotherapy are not as widely available. Furthermore, data comparing their effectiveness with well-established procedures like radiofrequency ablation is limited.

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“…RF ablation has been shown to be an effective treatment option for patients with primary and metastatic liver tumors, who are not surgical candidates due to tumor location, poor hepatic reserve, other comorbidities, or advanced age (6,14). Furthermore, RF ablation compares reasonably well with survival rates of surgery in patients with smaller (≤3 cm) tumors (7,15).…”

Section: Rf Ablation In Liver Tumorsmentioning

confidence: 99%

“…During energy application, the tip of the hydrodissection needle should be placed at least 1 cm away from the tip of the RF applicator. RF ablation of hepatic tumors is a relatively safe modality with a reported overall complication rate of 7.1% and a very low mortality (0.3%) (6). Immediate major complications include hemorrhage, biliary leakage or obstruction, infection, pneumothorax, and injury to adjacent organs (18,19).…”

Section: Rf Ablation In Liver Tumorsmentioning

confidence: 99%

“…In most cases, percutaneous RF ablation can be performed in patients under conscious sedation, by using medications similar to those used with any other interventional radiology procedure. In the clinical arena, RF ablation has been used for the treatment of various neoplasms, including metastases from a variety of primary tumors (4,5), such as hepatocellular carcinoma (HCC) (6,7), renal cell carcinoma (RCC) (8,9), non-small cell lung cancer (NSCLC) (10,11), and osteoid osteoma (12,13). In this article we review RF ablation techniques and their clinical implications.…”

mentioning

confidence: 99%

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Radiofrequency ablation: technique and clinical applications

Tatlı

Tapan²,

Morrison³

et al. 2011

Diagn Interv Radiol

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Radiofrequency ablation is the most commonly used percutaneous ablation technique and well-documented in the literature on focal therapies. It has become the image-guided ablation method of choice because of its efficacy, safety, and ease of use. Radiofrequency ablation has shown promise in treating selected solid tumors, particularly those involving the liver, kidneys, lungs, and the musculoskeletal system. It is a minimally invasive technique often used in inoperable patients with other comorbidities. Radiofrequency ablation requires a minimal hospital stay or can be performed on an outpatient basis. The aim of this article is to review radiofrequency ablation techniques and their clinical applications.

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Hepatic Radiofrequency Ablation

Cited by 141 publications

References 51 publications

RFA for Liver Tumors: Does It Really Work?

RFA for Liver Tumors: Does It Really Work?

Ablative techniques in hepatocellular carcinoma treatment

Radiofrequency ablation: technique and clinical applications

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