2001
DOI: 10.1016/s1072-7515(00)00778-x
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Hepatic Resection for Hepatocellular Carcinoma in The Elderly

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Cited by 108 publications
(76 citation statements)
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References 24 publications
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“…Previous studies addressing this issue have compared cohorts of elderly patients with younger patients treated in the same time period (Table 5). [6][7][8][9][10][11]18 However, comparing cohorts introduces a potential selection bias due to heterogeneity of patients and operative characteristics. In order to maximally reduce selection bias in this study, a matched control analysis was performed to ensure comparison of elderly and younger patients with the same diagnosis and the same extent of liver resection.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Previous studies addressing this issue have compared cohorts of elderly patients with younger patients treated in the same time period (Table 5). [6][7][8][9][10][11]18 However, comparing cohorts introduces a potential selection bias due to heterogeneity of patients and operative characteristics. In order to maximally reduce selection bias in this study, a matched control analysis was performed to ensure comparison of elderly and younger patients with the same diagnosis and the same extent of liver resection.…”
Section: Discussionmentioning
confidence: 99%
“…5 Nevertheless, several observational cohort studies addressed this issue and have failed to show age to be an independent risk factor influencing short-and long-term survival after liver resections. [6][7][8][9][10][11] These observational cohort studies included a mix of wedge, minor, and major liver resections, and retrospectively compared study groups based on patient age at the time of liver resection. This study design may include a selection bias in terms of diagnosis and magnitude of liver resection.…”
Section: Introductionmentioning
confidence: 99%
“…It should be noted that these data categorise patients according to the primary liver disease specified at the time of listing; this has the important implication that the 'HCC' category represents a minority of patients with tumours on 176,178,179,190,193,[415][416][417][418][419][420][421] • 11 insufficient sample size (n < 50) 171,172,186,205,411,[422][423][424][425][426][427] • Four included a substantial proportion of non-cirrhotic cases 155,165,428,429 • Five included a substantial proportion of large tumours (>5 cm) 166 …”
Section: Waiting List For Liver Transplantationmentioning
confidence: 99%
“…Hanazaki et al [21] also observe that cirrhosis and vascular invasion predict long term survival in patients older than 70 years. Vauthey et al [6] also confirm vascular invasion as a predictive factor for long term outcome but do not observe any significant correlation among survival and the presence of cirrhosis, grading, tumor dimension larger than 5 cm and free margins.…”
Section: Discussionmentioning
confidence: 95%