Hepatic trauma management and outcome; Our experience

Karim, Tanweer; Topno, Margaret; Reza, Ali; Patil, Kundan; Gautam, Raj; Talreja, Manish; Tiwari, Anupam

doi:10.1007/s12262-010-0054-z

Cited by 7 publications

(10 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The primary search identified 29 articles published between January 2000 and June 2014 that were screened (Figure 1) (10,11). A further 17 articles were excluded: 9 that amalgamated penetrating and blunt hepatic injury (4,(12)(13)(14)(15)(16)(17)(18)(19), 6 where the demographics characteristics and outcome of grade III to V blunt hepatic injury was not comprehensively depicted (20)(21)(22)(23)(24), and 2 included exclusively patients with juxtahepatic venous injury (25,26). admission was performed by NOM, TAE, and laparotomy in a median of 66% (range 0-100%), 3% (range 0-72%), and 31% (range 0-100%) of patients, respectively ( Table 1).…”

Section: Resultsmentioning

confidence: 99%

Management of severe blunt hepatic injury in the era of computed tomography and transarterial embolization

Melloul

Denys

Demartines

2015

Journal of Trauma and Acute Care Surgery

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Management of severe blunt hepatic injury in the era of computed tomography and transarterial embolization

Melloul

Denys

Demartines

2015

Journal of Trauma and Acute Care Surgery

View full text Add to dashboard Cite

show abstract

“…Traffic accidents in Turkey are the first and occupational accidents are the second leading causes of trauma-induced deaths [8]. Currently, the majority of solid organ injuries following blunt abdominal trauma can be successfully treated non-operatively [2,3].…”

Section: Discussionmentioning

confidence: 99%

“…As a result of its larger size and proximity to the ribs, the right lobe is injured more commonly than the left. Injuries to the liver occur in 35-45 % of patients with significant blunt abdominal trauma [2].…”

Section: Introductionmentioning

confidence: 99%

Effects of Copper, Zinc, and Vitamin Complex (Cernevit®) on Hepatic Healing in Rats Experimentally Subjected to Blunt Hepatic Trauma

et al. 2014

View full text Add to dashboard Cite

Solid organ injuries following blunt trauma are frequently encountered. The use of non-operative approach is gradually increasing. Thus, research on the methods that could enhance healing in solid organ injuries is in progress. Agents known to have antioxidant property were used after an experimentally induced blunt hepatic trauma. Thirty-two Wistar albino rats weighing 200 g were dropped from a height of 40 cm on to the right upper abdominal quadrant to produce a grade II-III hepatic injury. Rats were divided into control, Zn-administered, Cu-administered, and vitamin complexadministered groups, with eight rats in each. Aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels were measured in the blood samples. The percentage of cells displaying Ki-67 nuclear staining was estimated. The sections were stained with hematoxylin and eosin and the degree of inflammation in the samples was semiquantitatively assessed. Treatment with zinc, copper, and Cernevit® caused varying levels of decrease in AST, ALT, and LDH levels compared to the control group. Ki-67 positivity was significantly lower in group I compared with groups II and III (p=0.002). Ki-67 positivity was significantly higher in group II compared to the other groups (p<0.05). A marked improvement was observed in inflammation in group II. Copper and zinc treatment decreased inflammation as well as blood levels of AST and ALT, and enhanced the healing of traumatized hepatic tissue. However, Cernevit® reduced only the degree of inflammation.

show abstract

“…LMICs like India contribute to 90% of all the global injury burden, which is a critical public health issue [11]. Most published literature from India are anecdotal or single centre studies with small database [12][13][14][15][16]. A multi-centre hospital-based registry can help in better understanding the outcomes in the management of organ-speci c injuries.…”

Section: Introductionmentioning

confidence: 99%

Management of liver trauma in urban university hospitals in India: an observational multicentre cohort study

Sinha

Khajanchi²,

Prajapati³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background Low- and Middle-Income Countries (LMICs) contribute to 90% of injuries occurring in the world. Liver is the one of the commonest organ injured in abdominal trauma. This study aims to highlight the demographic and management profile of liver injury patients, presenting to four urban Indian university hospitals in India. Methods This is a retrospective registry-based study. Data of patients with liver injury either isolated or concomitant with other injuries was used using the ICD-10 code, S36.1 for liver injury. The severity of injury was graded based on the World Society of Emergency Surgery (WSES) grading for liver injuries. Results A total of 368 liver injury patients were analysed. 89% were males, with road traffic injuries being the commonest mechanism. As per World Society of Emergency Surgery (WSES) liver injury grade, there were 126 (33.7%) grade I, 87(23.6%) grade II, 67(18.2%) grade III & 88 (24.5%) grade IV injuries. The overall mortality was 16.6%. 262 patients (71.2%) were managed non-operatively (NOM) & 106 (38.8%) were operated. 90.1% of those managed non-operatively, survived. Conclusion In this multi-centre cohort of liver injury patients from urban university hospitals in India, the commonest profile of patient with a was a young male, with a blunt injury to the abdomen due to a road traffic accident. Success rate of non-operative management of liver injury is comparable to other countries.

show abstract

Hepatic trauma management and outcome; Our experience

Cited by 7 publications

References 16 publications

Management of severe blunt hepatic injury in the era of computed tomography and transarterial embolization

Management of severe blunt hepatic injury in the era of computed tomography and transarterial embolization

Effects of Copper, Zinc, and Vitamin Complex (Cernevit®) on Hepatic Healing in Rats Experimentally Subjected to Blunt Hepatic Trauma

Management of liver trauma in urban university hospitals in India: an observational multicentre cohort study

Contact Info

Product

Resources

About