Hepatic tumors in children: ultrasonic differentiation of malignant from benign lesions.

Brunelle, Françis; P, Chaumont

doi:10.1148/radiology.150.3.6695069

Cited by 31 publications

(12 citation statements)

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“…In addition, sonography recently has demonstrated patency of the portal veins in children with real-time sector scanning in our series as well as other series [15].…”

Section: Malignant Tumorssupporting

confidence: 78%

The continued value of angiography in planning surgical resection of benign and malignant hepatic tumors in children

1988

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We assessed the accuracy of angiography or digital subtraction angiography (DSA) in diagnosing malignancy in hepatic tumors in children. In addition, these results were correlated with sonographic and computed tomographic findings of the liver in selected patients. Twenty-seven patients with primary liver tumors were examined with celiac or selective hepatic arteriography. Sonography was performed in 15 and computed tomography in 15 of the 27 patients. Angiographic criteria for malignancy or benignancy were established. These findings were correlated with computed tomographic and sonographic findings of the liver vascularity in selected patients. The final pathologic diagnosis was established surgically or by percutaneous biopsy. Sonography and computed tomography can be used as the initial procedure for evaluating tumor size, location and hepatic vascularity. However, the exact vascular anatomy demonstrated by angiography in children is more accurate and is often needed prior to surgical resection of primary liver tumors.

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“…In addition, sonography recently has demonstrated patency of the portal veins in children with real-time sector scanning in our series as well as other series [15].…”

Section: Malignant Tumorssupporting

confidence: 78%

The continued value of angiography in planning surgical resection of benign and malignant hepatic tumors in children

1988

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“…The more or less high signal in T2 weighted sequence and the bad limited aspect of the tumor are suggestive of a malignant liver tumor. However, MRI aspects are not very specific of MMT [9,10,12]. In fact, MRI can mostly be a valuable guide for the surgeon before the surgical procedure.…”

Section: Radiological Diagnosismentioning

confidence: 99%

Primitive malignant nonepithelial hepatic tumors in children

Babin-Boilletot

Flamant

Terrier‐Lacombe³

et al. 1993

Med. Pediatr. Oncol.

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Primary intrahepatic malignant nonepithelial tumors are very rare in children and account for 2% of all malignant mesenchymatous tumors under the age of 15 years. Clinical presentation, radiologic features, and histologic types are not unequivocal. The predominant role of surgery takes place either initially in small localized tumors or later, after initial reductive chemotherapy. In all cases, complete resection is the necessary but not sufficient condition for cure. Additional radiotherapy seems ineffective. High-dose chemotherapy and/or liver transplantation can be proposed for resistant cases. The disease-free survival rate is 37% at 2 years for the whole series.

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“…Malignant tumors are usually echogenic as compared to normal liver [5] and may be non-homogeneous with hypoechogenic areas [6]. The best sign to differentiate benign lesions from malignant lesions is portal thrombosis [7]. We do not think that there is any specific echographic sign to differentiate the different types of malignant tumor.…”

Section: Discussionmentioning

confidence: 93%

Ultrasonography and computed tomography for diagnosis and follow-up of biliary duct rhabdomyosarcomas in children

et al. 1987

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The authors report eight cases of biliary duct rhabdomyosarcoma in children, examined by US and CT. There were five boys and three girls, aged 2 to 17 years. At presentation, US demonstrates the tumor mass within the liver or the hepatic hilum; it allows measurement of it and defines the relationship with portal vessels, biliary tract and other important structures. CT complements the US evaluation and determines operability. As US and CT cannot assess the histological origin of the tumor, a biopsy is mandatory before treatment. If complete surgical excision does not seem possible, percutaneous biopsy is preferable to incomplete excision and its possible complications. During the follow-up period, US can be repeated to measure tumor regression under chemotherapy. After surgery, CT seems preferable because of gas interposition. Both US and CT proved to be valuable for the early detection of local recurrence. The prognosis of these tumors remains bad. However, with more aggressive and hopefully more efficient chemotherapy a precise evaluation of the tumor extension by US and CT is very important. Surgery will then be performed only on localized tumors or on residual masses after chemotherapy.

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Hepatic tumors in children: ultrasonic differentiation of malignant from benign lesions.

Cited by 31 publications

References 0 publications

The continued value of angiography in planning surgical resection of benign and malignant hepatic tumors in children

The continued value of angiography in planning surgical resection of benign and malignant hepatic tumors in children

Primitive malignant nonepithelial hepatic tumors in children

Ultrasonography and computed tomography for diagnosis and follow-up of biliary duct rhabdomyosarcomas in children

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