“…The incidence of major complications has been reported to be less than 5%, including hepatic insufficiency, liver abscess, parenchymal infarction, intrahepatic aneurysm, pulmonary embolism, ischemic cholecystitis or gallbladder infarction, bone marrow depression, liver rupture, and gastric or duodenal ulceration [340]. Important predisposing factors are major portal vein obstruction, compromised hepatic functional reserve, biliary obstruction, previous biliary surgery, excessive amount of iodized oil, and nonselective embolization [341]. TACE does not induce significant liver dysfunction in patients with C-P class A or B cirrhosis despite embolization of relative proximal hepatic arteries [342].…”