Hepatic vasculitis mimicking liver abscesses in a patient with systemic lupus erythematosus

Alanazi, Thari; Alqahtani, Mohammad; Duraihim, Huda Al; Khathlan, Khalid Al; Ahmari, Bader Al; Makanjuola, Dorothy; Afzal, Mohammed

doi:10.4103/0256-4947.57172

Cited by 18 publications

(13 citation statements)

References 11 publications

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“…Necrotizing arteritis of the liver has been reported in 18–20% of SLE autopsy cases [ 63 , 64 ]. Alazani et al described a hepatic vasculitis mimicking multiple liver abscesses in a patient with SLE, which showed clinical improvement after steroid therapy [ 65 ]. Spontaneous hepatic rupture due to small- and medium-sized vessel vasculitis is an unusual complication [ 66 , 67 ].…”

Section: Gastrointestinal Vasculitismentioning

confidence: 99%

Lupus Vasculitis: An Overview

et al. 2021

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Lupus vasculitis (LV) is one of the secondary vasculitides occurring in the setting of systemic lupus erythematosus (SLE) in approximately 50% of patients. It is most commonly associated with small vessels, but medium-sized vessels can also be affected, whereas large vessel involvement is very rare. LV may involve different organ systems and present in a wide variety of clinical manifestations according to the size and site of the vessels involved. LV usually portends a poor prognosis, and a prompt diagnosis is fundamental for a good outcome. The spectrum of involvement ranges from a relatively mild disease affecting small vessels or a single organ to a multiorgan system disease with life-threatening manifestations, such as mesenteric vasculitis, pulmonary hemorrhage, or mononeuritis multiplex. Treatment depends upon the organs involved and the severity of the vasculitis process. In this review, we provide an overview of the different forms of LV, describing their clinical impact and focusing on the available treatment strategies.

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Section: Gastrointestinal Vasculitismentioning

confidence: 99%

Lupus Vasculitis: An Overview

et al. 2021

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“…Various forms of hepatic pathology related to SLE have been described, including fatty liver, chronic persistent hepatitis, portal inflammation, hepatic vasculitis, and granulomatous hepatitis. Although these liver abnormalities may have been related to SLE, the majority of the biochemical abnormalities seen in these studies were usually secondary to other causes such as drug-induced liver dysfunction, alcoholic liver disease, congestive heart failure, infection, or metabolic disturbances 7. NLE liver disease may present as an isolated disorder or in association with other manifestations of NLE 8…”

Section: Discussionmentioning

confidence: 89%

Early Cholestasis in Neonatal Lupus Erythematosus

2011

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“…Although these liver abnormalities may have been related to SLE, the majority of the biochemical abnormalities seen in these studies were usually secondary to other causes such as drug-induced liver dysfunction, alcoholic liver disease, congestive heart failure, infection, or metabolic disturbances. 7 NLE liver disease may present as an isolated disorder or in association with other manifestations of NLE. 8 …”

Section: Discussionmentioning

confidence: 99%

Early cholestasis in neonatal lupus erythematosus

Shahian

Khosravi

Anbardar

2011

Annals of Saudi Medicine

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Neonatal lupus erythematosus is an immune-mediated disease caused by transplacental passage of maternal autoantibodies, primarily anti-Ro (SSA) and anti-La (SSB). The major clinical manifestations are congenital heart block, cutaneous lupus lesions, and hematologic problems. Hepatic, pulmonary, and neurological involvements are rare. We report a 5-day-old male neonate, born to a clinically asymptomatic mother, presenting with conjugated hyperbilirubinemia, cutaneous lupus lesions, congenital heart block, and thrombocytopenia. Both the neonate and his mother had high titers of antinuclear antibodies (1:640), anti-Ro (SSA), and anti-La (SSB) antibodies. The thrombocytopenia improved with prednisolone (2 mg/kg/day) for 14 days. The skin lupus rashes and bilirubin resolved 2 months later, and liver enzymes were completely normal by 6 months.

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Hepatic vasculitis mimicking liver abscesses in a patient with systemic lupus erythematosus

Cited by 18 publications

References 11 publications

Lupus Vasculitis: An Overview

Lupus Vasculitis: An Overview

Early Cholestasis in Neonatal Lupus Erythematosus

Early cholestasis in neonatal lupus erythematosus

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