Hepatic vein waveform and splenomegaly predict improvement of prothrombin time after splenectomy in hepatitis C virus‐related cirrhotic patients

Abstract

Prothrombin time and total bilirubin improve in approximately half of cirrhotic patients within a year after splenectomy. HVWF type I and splenomegaly may be predictive factors for improvement in prothrombin time after splenectomy in patients with cirrhosis due to hepatitis C.

Impact of Splenic Volume and Splenectomy on Prognosis of Hepatocellular Carcinoma Within Milan Criteria After Curative Hepatectomy

“…We found both late and early recurrence rates were higher in the high SV than the low SV group. Taken together, the present findings and those of previous reports suggest that SV is correlated with liver dysfunction [7, 26, 27]. Furthermore, other studies have shown that PH is associated with an increased incidence of HCC [32, 33].…”

“…Kinjo et al showed that after splenectomy, portal flow decreases more markedly in patients with large spleens than in those with small spleens. Some other studies have suggested that liver function improves more markedly in patients with larger spleens [26, 27]. Previous studies have shown that adding splenectomy to hepatectomy in patients with HCC and hypersplenism does not improve overall survival [16, 17].…”