Hepatitis A immunisation in persons not previously exposed to hepatitis A

Patterson, Jenna; Irving, Greg J; Li, Yu Qi; Yue, Jiang; Mearns, Helen; Pope, Daniel; Muloiwa, Rudzani; Hussey, Gregory; Kagina, Benjamin M.

doi:10.1002/14651858.cd013500

Cited by 1 publication

(1 citation statement)

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“…Developed countries have adopted the universal vaccination program, resulting in the control of HAV. Two vaccine forms are available against HAV: live-attenuated and inactivated (Patterson et al 2019). Inactivated vaccines are the most commonly used in developing and some developed countries.…”

Section: Active Immunization / Vaccinationmentioning

confidence: 99%

Hepatitis A: An Overview

2023

IJAB

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Hepatitis A, caused by the hepatitis A virus (HAV), remains a consequential global public health concern. This chapter provides a comprehensive overview of the virology, pathogenicity, zoonotic transmission, epidemiology, clinical manifestations, and prevention strategies associated with hepatitis A. Hepatitis A is caused by non-enveloped virus belongs to the family Picornaviridae. It has a limited scope for zoonotic transmission, but it is widely distributed in human population with varying prevalence rates across different regions. Factors such as contaminated food and water sources, and crowded living conditions with poor sanitation contribute to the transmission of the virus. The disease predominantly affects low and middle-income countries, emphasizing the understanding of its socio-economic implications. Clinical features of hepatitis A range from asymptomatic infections to severe liver disease. The virus primarily targets the liver, leading to symptoms such as jaundice, fatigue, nausea, and abdominal pain. Vulnerable populations, including young children and older adults, are at a higher risk of getting severe complications. Timely diagnosis through serological testing is crucial for proper public health management and interventions. Prevention strategies play a pivotal role in controlling the spread of hepatitis A. Vaccination campaigns targeting high-risk populations have proven to be effective in reducing the incidence of infection rate. In conclusion, hepatitis A remains a significant challenge with diverse clinical presentations and global distribution. By fostering a deeper comprehension of the virus and its modes of transmission, healthcare professionals, policymakers, and researchers can contribute to the development of effective strategies to mitigate the impact of Hepatitis A on public health. Ongoing efforts to enhance vaccination coverage, improve sanitation infrastructure on individual and public level, and raise awareness about hygienic practices are crucial for reducing the burden of hepatitis A and preventing its associated complications.

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Section: Active Immunization / Vaccinationmentioning

confidence: 99%

Hepatitis A: An Overview

2023

IJAB

View full text Add to dashboard Cite

show abstract

Hepatitis A immunisation in persons not previously exposed to hepatitis A

Cited by 1 publication

References 50 publications

Hepatitis A: An Overview

Hepatitis A: An Overview

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