Hepatitis B Reactivation in Immunosupressed Patients,  Prophylaxis and Management

Kholili, Ulfa; Yanti, Tri Yanti Tri

doi:10.24871/182201798-103

Cited by 1 publication

(1 citation statement)

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“…Hepatitis B reactivation clinically varies from asymptomatic elevation of serum ALT to acute liver failure and death. 6 The occurrence of hepatitis B reactivation in HCC conditions is directly related to poor survival of HCC. To date, information on hepatitis B virus reactivation in negative HbsAg patients with HCC is limited to case reports or small case series.…”

Section: The Indications Of Therapy In Hepatitis B Infection Depend O...mentioning

confidence: 99%

The Management Problems of Patient with Chronic Hepatitis B Infection and Its Reactivation

Imro'ati

Maimunah

2020

InaJGHE

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Hepatitis B virus infection is a major global health problem in the world and particularly in Indonesia. It can cause chronic infection and puts people at high risk of death from cirrhosis and liver cancer. In this case, we will show about the problems that may occur while we manage a patient. A 55 years old man with chronic hepatitis B has been treated with Telbivudin 600 mg for 8 years and and then stop for 2 years (The HBsAg has been non reactive, HBeAg has been seroconversion from positive to negative, and HBV DNA has been not detected since 2014 until January 2016). In 2018, patients undergo surgery to remove nodules in the liver. After that, there were transaminase and bilirubin elevation, and then HBsAg become reactive again. After giving combination therapy of Telbivudin 600 mg with Entecavir 0.5 mg and metyl prednisolone 8 mg (per os, three times a day) for 1 months, the transaminase became decrease, but the bilirubine was still high. The patient was reported to have died in February 2019 after being hospitalized in a hospital outside Java, so we could not know or investigasted the cause of his mortality.

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Section: The Indications Of Therapy In Hepatitis B Infection Depend O...mentioning

confidence: 99%

The Management Problems of Patient with Chronic Hepatitis B Infection and Its Reactivation

Imro'ati

Maimunah

2020

InaJGHE

View full text Add to dashboard Cite

show abstract

Hepatitis B Reactivation in Immunosupressed Patients, Prophylaxis and Management

Abstract: Hepatitis B virus (HBV) reactivation is a clinical problem associated with high morbidity and mortality rates. Currently, this incidence seems to be increasing around the world. The reactivation commonly developes in immunosuppressed individuals

Cited by 1 publication

References 10 publications

The Management Problems of Patient with Chronic Hepatitis B Infection and Its Reactivation

The Management Problems of Patient with Chronic Hepatitis B Infection and Its Reactivation

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