Hepatitis B screening in a Northern Irish mental handicap institution: relevance to hepatitis B vaccination

Kee, Frank; McGinnity, M.; Marriott, C.; Calvert, G J; O’Neill, Hugh J.; Connolly, J. H.

doi:10.1016/0195-6701(89)90039-x

Cited by 4 publications

(5 citation statements)

References 20 publications

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“…[25] Nigeria is reported among nation in hyper-endemic zone for hepatitis B viral infection and the prevalence varies from different part of this country. The prevalence of hepatitis B in Nigeria is put between 9 and 39% [7,8,26] In this present study, the sero-prevalence of hepatitis B is 10 and 10.9% among MII and BDs, respectively, though there was no statistically significant difference when compared with prevalence among the blood donors (P > 0.05), these findings further confirmed Nigeria as a hyper-endemic zone for hepatitis B infection. The prevalence of HBV in this study was high both in the mentally ill and the blood donors but fell within the national prevalence figure of 9-39% of the population.…”

Section: Discussionsupporting

confidence: 88%

“…The reason for the high prevalence of HBV infection in Nigeria has been previously said to be due to late inclusion of HBV immunization in the National Program on Immunization (NPI) in 2003 and despite this the vaccine is not widely available. [26] More of blood donors consumed alcohol, smoked cigarette than MII, might be the facts that MII are on follow-up and under close supervision. The MII was engaged in extramarital sex, homosexuality, and sex trade and had received more blood transfusion than the BDs and these probably contributed to the prevalence recorded.…”

Section: Discussionmentioning

confidence: 95%

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Sero-prevalence of hepatitis B and C among mentally ill patients attending a tertiary hospital in Nigeria

et al. 2014

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 95%

Sero-prevalence of hepatitis B and C among mentally ill patients attending a tertiary hospital in Nigeria

et al. 2014

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“…The frequency of HBsAg seropositivity found in our psychiatric population was also much higher than those reported in Mexican blood donors [15-17]. When comparing our results with those reported in similar psychiatric populations of other countries, our frequencies were only comparable with that found in northern Ireland [10]. However, our figure was much lower than those reported in Brazil [8], the U.S.A. [11], Spain [9], Singapore [13], and Taiwan [12].…”

Section: Discussionsupporting

confidence: 59%

“…In European countries, a study carried out in Spain showed that HBV seropositivity in mentally handicapped adults was 81.3% [9]. In contrast, in Northern Ireland, only 4.5% of the residents of an institution for the mentally handicapped carried any HBV marker [10]. In the U.S.A., a study performed on people with severe mental illness showed a 23.4% prevalence rate of HBV infection [11].…”

Section: Introductionmentioning

confidence: 99%

Untitled

Esquivel

Valenzuela

M³

et al. 2005

Clin Pract Epidemiol Ment Health

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BackgroundThe epidemiology of the hepatitis B virus (HBV) infection in psychiatric patients from developing countries is poorly studied. Therefore, we sought to determine the frequency of HBV surface antigen (HBsAg) and HBV surface antibody (HBsAb) serological markers of HBV infection in a population of patients of a psychiatric hospital in Durango City, Durango, Mexico, and to determine whether there are any epidemiological characteristics of the subjects associated with the infection.MethodsOut of 150 patients of the psychiatric hospital of Durango City, 99 were examined for HBsAg and HBsAb by AUSZYME MONOCLONAL (Abbott Laboratories, Abbott Park, IL, USA) assay and AUSAB (Abbott Laboratories, Abbott Park, IL, USA) assay, respectively. Epidemiological data from each participant was also obtained. For comparison purposes, 2505 blood donors were examined for HBsAg seropositivity.ResultsOut of the 99 patients studied, twelve showed serological evidence of HBV infection (12.1%); 7 of them (7.1%) were positive for HBsAg, and 5 (5.1%) were positive for HBsAb. Out of the 2505 blood donors, 2 (0.0008%) were HBsAg positive. Seropositivity to HBV markers was associated with an age of 45 years and older (OR = 4.27; 95%CI = 1.02–18.78). Other characteristics as gender, number of hospitalizations, duration of the last hospitalization, and clinical diagnosis were not associated with seropositivity to HBV infection markers. Patients showed a significantly higher HBsAg seropositivity than blood donors (p < 0.0000001)ConclusionHBV was found to be an important infectious agent in the Mexican psychiatric inpatient population studied. Health care strategies for prevention and control of HBV infection in psychiatric hospitals should pay special attention to patients aged forty-five years and older.

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“…1982;Lohiya er al. 1986), while others have rates of less than 5% (Kee et al 1989; Thomson et al 1989). In some centres, there is active transmission of hepatitis B; however, in others, it appears to be 'burnt out' (Clarke et al 1984).…”

Section: Introductionmentioning

confidence: 99%

Hepatitis B in the non‐residential mentally handicapped population

Devlin

Mulcahy²,

Corcoran

et al. 1993

J intellect Disabil Res

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This study describes seroprevalence and risk factors for hepatitis B in seven centres caring for non‐residential mentally handicapped individuals. Overall, 11% were hepatitis B marker seropositive and 4% had the hepatitis B surface antigen (HBsAg). Male sex and increasing age were associated with seropositive status, and Down's syndrome was associated with the presence of HBsAg. Immediate family members of those with hepatitis B markers were screened and 22% had evidence of heptatitis B markers. Forty‐one family members were identified when the mentally handicapped individual was HBsAg positive and of these 13 (32%) were seropositive. This study demonstrates that hepatitis B is a problem for the non‐residential mentally handicapped population and confirms the risk of infection to their immediate families.

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Hepatitis B screening in a Northern Irish mental handicap institution: relevance to hepatitis B vaccination

Cited by 4 publications

References 20 publications

Sero-prevalence of hepatitis B and C among mentally ill patients attending a tertiary hospital in Nigeria

Sero-prevalence of hepatitis B and C among mentally ill patients attending a tertiary hospital in Nigeria

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Hepatitis B in the non‐residential mentally handicapped population

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