2024
DOI: 10.1111/sji.13402
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Hepatitis B vaccine responders show higher frequencies of CD8+ effector memory and central memory T cells compared to non‐responders

Mahsa Eshkevar Vakili,
Niloofar Mashhadi,
Mohammad Reza Ataollahi
et al.

Abstract: Hepatitis B (HB) infection is a major global health problem. There is limited knowledge about HB vaccination‐induced immune memory responses. We compared the frequency of CD8+ memory T cell subsets between responders (RSs) and non‐responders (NRs) to HB vaccination. Blood samples were collected from RSs and NRs. PBMCs were cultured in the presence of Hepatitis B surface antigens (HBsAg) and PHA for 48 h to restimulate CD8+ memory T cells and T cell memory subsets were detected by flow cytometry using memory ce… Show more

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