Hepatitis B Vireamia in Hepatitis B Surface Antigenemic Patients in Bangladesh

Abstract

Objectives: This study evaluates the distribution of hepatitis B vireamia in patients with hepatitis B virus (HBV) infection. Methods: HBV-infected patients were enrolled in this study. HBV DNA tests were carried out using Smart Cycler II to detect HBV DNA level in serum samples of all HBsAg-positive patients. Results: The distribution of HBV DNA level was found significantly related to age groups (p<0.05), gender group (p<0.05), ALT group (p<0.05), and HBeAg group (p<0.05). The HBV DNA level was recorded to be significantly higher in the HBeAg-positive group (p<0.05) in compared to the HBeAg-negative group. Conclusions: A low level of viral replication may persevere in chronic HBV-infected patients who are HBeAg-negative, and the level of HBV DNA was higher in the HBeAg-positive group.

Hepatitis B Vaccination Outcomes and Broad Spectrum of Hepatitis B Infections in Nigeria: An Evidence-Based Picture

“…Hepatitis B viral markers screening rather than HBsAg is a good entry point of testing in early diagnosis of HBV infection [51] . Besides giving the broad revelations on different phases of HBV infection and showing evidence of immune protection in vaccinated research participants, it ensures relative ease in the monitoring of chronically infected individuals by circumventing the associated delays in follow-up.…”