Hepatitis B virus infection and its determinants among HIV positive pregnant women: Multicenter unmatched case-control study

Anteneh, Zelalem Alamrew; Wondaye, Estifanose; Mengesha, Endalkachew Worku

doi:10.1371/journal.pone.0251084

Cited by 9 publications

(9 citation statements)

References 34 publications

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“…This research is in accordance with the research done by Anteneh and colleagiues where after univariate analysis, the results revealed no relationship between level of education and the Hepatitis B virus infection in HIV/AIDS patients pregnant women with pvalue of 0.39 (p-value=0.39) and OR=4.2, this results implies no relationship among Hepatitis B virus infected individuals who are also ©2022, JEKK, All Right Reserved Infected with HIV/AIDS in pregnant women in Ethiopia 16 .…”

Section: Level Of Educationsupporting

confidence: 89%

Influence of Epidemiological Risk Factors for Occurrence of Hepatitis B Virus (HBV) Co-Infection in HIV/AIDS Patients: (Study in dr. Kariadi Hospital, Semarang, Indonesia)

Wang

Hadisaputro

Sofro

et al. 2022

Comm. Health. Epid. J

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Background: Chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma are all have a major cause which is Hepatitis B virus (HBV). Given the fact that HIV and HBV are all transmitted through the same routes, co-infection is common. The objective of this research is to identify several risk factors which influence the occurrence of Hepatitis B virus infection in HIV/AIDS patients at Kariadi, Semarang, Indonesia. Method: This research is analytical observational with a case control study design, a sample of 68(34 cases and 34 controls) For all HIV patients involved in the study, samples were determined by a positive HBsAg test, The dependent variable is HBV occurrence in HIV/AIDS individuals and dependent variable were CD4≤100, Age>30,gender,marital status ,level of education ,male who have sex with other male(MSM),Analysis of data was done through univariate, bivariate and multivariate analysis with logistic regression.Result: Variables that were proven to influence the occurrence HBV infection in HIV/AIDS individuals, after analysis were CD4≤100(p= 0.003 OR=7.535, 95% CI=(2.029-27.990 ) , being male who do sex with male( MSM) (P=0.027 ,OR=3.544 ,95%CI=( 1.158-10.848) . The probability for HIV/AIDS patients to be infected by HBVirus when they have both these risk factors is equal to 88.18%.Conclusion: The factors that were proven to affect the influence of occurrence Hepatitis B virus in HIV/AIDS patients were, CD4≤100 and being male who do sex with other male (MSM).

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Section: Level Of Educationsupporting

confidence: 89%

Influence of Epidemiological Risk Factors for Occurrence of Hepatitis B Virus (HBV) Co-Infection in HIV/AIDS Patients: (Study in dr. Kariadi Hospital, Semarang, Indonesia)

Wang

Hadisaputro

Sofro

et al. 2022

Comm. Health. Epid. J

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“…Similarly, a study conducted in Nigeria noted that sexually active adults with STIs are at high risk of acquiring Hepatitis B viral infections [17]. Agrawal et al and Govindan et al found a lower prevalence of HBV among patients infected with syphilis [18, 19], other studies have noted a high prevalence of syphilis, HIV, HCV and Hepatitis B co-infection [20, 21, 22, 23, 24, 25, 26].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Hepatitis B viral infection and associated factors among adults in Moyo district, North-Western Uganda

Lulu

Alege

2022

Preprint

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Background Hepatitis B viral infection is a public health problem and estimates show that about 30% of the world’s population is infected with the virus, with about 350 to 400 million of them remaining chronically infected. Northern Uganda has the highest prevalence of HBV in Uganda. In this study, we sought to establish factors influencing the prevalence of Hepatitis B viral infection among adults in Moyo district, North-Western Uganda. Methods We used a descriptive cross-sectional study where quantitative data collection methods and analysis was employed. Self-reported HBV infection by respondents who had test result forms diagnosed with HBV within the last one year was reviewed by the researchers to confirm whether the respondent was negative or positive with Hepatitis B. 384 samples were determined using Cochran (1963:75) and a multi-stage sampling technique was used. Bivariate and multivariate analyses were done using SPSS (20.0). Results Out of the 384 respondents interviewed, 29 (7.6%, 95%CI: 5.1-10.7) had HBV. Factors influencing the prevalence of HBV were; level of education (p=0.047*), ever having had STIs (aOR=18.090, 95%CI=5.699-57.426, p=0.000*), Health facilities have equipment for screening HEP B viral infection ANC (aOR=10.762, 95%CI=1.316-88.027, p=0.027*) were statically significant in influencing the prevalence of HBV, while the number of sexual partners ever had (p=0.984) was not statistically significant in influencing the prevalence of Hepatitis B viral infection. Conclusion We found a high prevalence of HBV among adults in Moyo district in North-Western Uganda compared to the national prevalence. Key influences of HBV prevalence included education level, ever being infected with any other STIs (HIV, Syphilis, gonorrhoea), multiple sexual partners and presence of HBV screening equipment at the health facilities. Need for more emphasis on HBV childhood immunization, screening, vaccination of adults, other preventive measures and treatment of those already infected.

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“… 44 A recent study revealed that pregnant women with HBV infection had a threefold increased risk for anemia compared with those with human immune virus‐positive status but without HBV infection. 45 One large cohort study has found a strong association between HBV infection and incident thrombocytopenia. 46 Early detection of hepatitis B virus infection before pregnancy should be considered in clinical practice, and cautious surveillance must be performed.…”

Section: Discussionmentioning

confidence: 99%

“…A previous study has shown that the presence of anemia in patients with HBV infection could indicate alterations in liver function 44 . A recent study revealed that pregnant women with HBV infection had a threefold increased risk for anemia compared with those with human immune virus‐positive status but without HBV infection 45 . One large cohort study has found a strong association between HBV infection and incident thrombocytopenia 46 .…”

Section: Discussionmentioning

confidence: 99%

Prevalence of hepatitis B virus infection among pregnant women in the mountainous regions of southern China: A retrospective single‐center study

Deng

Lin

Guo

et al. 2023

Clinical Laboratory Analysis

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Background Hepatitis B virus (HBV) infection remains a major public health issue worldwide. Moreover, its prevalence varies significantly in different geographic areas of China. The current study aimed to assess the prevalence of HBV infection among Hakka pregnant women in Meizhou, a remote mountainous region in southern China. Methods This research was performed between January 2015 and December 2020. In total, 16,727 pregnant women receiving antenatal care at Meizhou People's Hospital were included in the analysis. All pregnant women were screened for serum HBV markers. Results The prevalence rates of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody positivity among the participants were 11.74% ( n = 1964) and 48.00% ( n = 8029), respectively. The overall prevalence rates of susceptibility to infection, HBV immunity, previous/occult infection, inactive HBsAg carrier, and active infection were 36.16%, 33.61%, 16.94%, 8.11%, and 2.30%, respectively. According to age distribution, the prevalence rate of HBsAg positivity elevated concomitantly with increasing age ( p < 0.001). From 2015 to 2020, the prevalence rate of HBsAg positivity decreased from 14.50% to 8.19% and that of hepatitis B pre‐core antigen positivity from 4.42% to 2.31%. In addition, pregnant women with HBsAg‐positive status were more likely to present with gestational diabetes, thrombocytopenia, and anemia than those with HBsAg‐negative status. Conclusion The HBV infection rate remains high among pregnant women in the indigenous Hakka population in southern China. To prevent vertical transmission, cautious surveillance of maternal HBV infection status should be considered in Hakka pregnant women in Meizhou.

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Hepatitis B virus infection and its determinants among HIV positive pregnant women: Multicenter unmatched case-control study

Cited by 9 publications

References 34 publications

Influence of Epidemiological Risk Factors for Occurrence of Hepatitis B Virus (HBV) Co-Infection in HIV/AIDS Patients: (Study in dr. Kariadi Hospital, Semarang, Indonesia)

Influence of Epidemiological Risk Factors for Occurrence of Hepatitis B Virus (HBV) Co-Infection in HIV/AIDS Patients: (Study in dr. Kariadi Hospital, Semarang, Indonesia)

Prevalence of Hepatitis B viral infection and associated factors among adults in Moyo district, North-Western Uganda

Prevalence of hepatitis B virus infection among pregnant women in the mountainous regions of southern China: A retrospective single‐center study

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