Hepatitis C virus induces nasal epithelial erosion and sub-epithelial rhinitis

Abstract

HCV induces histopathological rhinitis with nasal epithelial erosion. However, it does not seem that the nasal tissue harbors the virus.

Characterization of hepatitis C virus‐induced nasal mucosa remodelling

“…Sir : We recently reported that hepatitis C virus (HCV) infection induces mild to moderate nasal fibrosis and epithelial erosion but with subclinical rhinitis 1 . To further characterize HCV‐induced nasal nucosa remodelling, nine patients participated in the current study.…”

Extrahepatic Nasal Manifestations of Hepatitis C Virus

“…This opened a channel for an important question why do these patients develop recurrent epistaxis despite normal coagulation profile. This was at least partially answered in a study that reported that HCV infection induces mild to moderate nasal fibrosis and epithelial erosion but with subclinical rhinitis [2]. In this article the authors investigated nasal biopsies from 20 patients, presenting with recurrent epistaxis with HCV infection but with no liver cirrhosis and with normal liver function tests, and from 10 control subjects.…”