Hepatitis C virus infection and alanine transaminase levels in the general population: a survey in a southern Italian town

Maio, Giuseppe Di; D’Argenio, Paolo; Stroffolini, Tommaso; Bozza, A.; Sacco, Lea; Tosti, Maria Elena; Intorcia, Michele; Fossi, Elena; D’Alessio, Giovanna; Kondili, Loreta A.; Rapicetta, Maria; Mele, Alfonso

doi:10.1016/s0168-8278(00)80167-1

Cited by 128 publications

(109 citation statements)

References 11 publications

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“…Indeed, the most commonly identified genotypes (1b, 2a/2c) are the same as those identified most frequently in the general population in Italy, according to several seroepidemiologic population-based studies. [26][27][28][29] These results are consistent with those of a previous study on HCV prevalence among patients with lymphoproliferative disorders in whom no association with a specific HCV genotype was found. 5 In 2 studies, however, genotype 2a was more common among patients with monoclonal gammopathy than in patients without this disease.…”

Section: Discussionsupporting

confidence: 91%

Hepatitis C virus and B-cell non-Hodgkin lymphomas: an Italian multicenter case-control study

Mele

Pulsoni

Bianco

et al. 2003

Blood

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267

201

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Section: Discussionsupporting

confidence: 91%

Hepatitis C virus and B-cell non-Hodgkin lymphomas: an Italian multicenter case-control study

Mele

Pulsoni

Bianco

et al. 2003

Blood

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267

201

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“…In contrast, Mele et al (6) did not observe any difference in the distribution of HCV genotypes between Italian B-cell NHL patients and control subjects. The HCV genotype distribution observed among both groups was similar to previous estimates of the HCV genotype distribution among the Italian population (18)(19)(20).…”

Section: Prevalence Of Anti-hcv Abs And/or Hcv-rna and Hcv Genotypes supporting

confidence: 88%

Extrahepatic disorders of HCV infection: A distinct entity of B-cell neoplasia?

et al. 2010

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Abstract. Some infectious agents have been associated with B-cell lymphoma development. In the last decades, it has been demonstrated that patients infected by hepatitis C virus (HCV) are more likely to develop B-cell non-Hodgkin's lymphoma (NHL) than those uninfected. The prevalence of HCV-infection among NHL patients is reported in this review of all Italian studies on NHL and HCV infection, both case-control and case series. From 18 studies, the prevalence of anti-HCV antibodies in 2736 NHL patients was 19.7% (range: 8.3-37.1%). The association of HCV-infection with each NHL histotype in case-control studies is discussed. Molecular mechanisms by which HCV infection promotes B-cell NHL development is also explored and indicate that HCV-associated lymphomas may be a distinct entity. Clarification of these mechanisms may improve diagnosis, classification and therapy of this subset of NHL. Finally, treatment of HCV-positive patients with lymphoproliferative disorders are herein summarized and further support the notion that HCV infection contributes to the development of these pathologic conditions.

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“…Testing for hepatitis C should be undertaken in patients with abnormal aminotransferases and/or risk factors for contracting hepatitis C. These risk factors include past or active IDU, blood transfusion before the introduction of second-generation anti-HCV assays in 1991, and immigration from countries of high prevalence where medical procedures may have been dispensed using improperly sterilized needles or unscreened blood products (8,9). The initial test should be an antibody test against HCV (third-generation enzyme-linked immunoassay).…”

Section: Chronic Hepatitis Cmentioning

confidence: 99%

Management of Chronic Hepatitis C: Consensus Guidelines

Sherman

Shafran

Burak

et al. 2007

Canadian Journal of Gastroenterology

102

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Since the last consensus conference on the management of chronic viral hepatitis, a number of studies looking at modifications of the standard course of treatment have been published. These changes have been sufficiently substantive to warrant review to determine whether any changes in the recommended treatment algorithms are needed. A consensus development conference was held in January 2007, and the present document highlights the results of the presentations and discussion about these issues. It reviews the epidemiology of hepatitis C in Canada, treatment of acute hepatitis C and new algorithms in chronic hepatitis C, including retreatment of previous treatment failures. In addition, sections on management of hepatitis C in special populations have been updated. There is also a section on the use of hematopoietic growth factors to help manage patients on therapy. The document should be read in conjunction with the previous document to identify changes. Some recommendations made in the previous document remain and are not discussed here.

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Hepatitis C virus infection and alanine transaminase levels in the general population: a survey in a southern Italian town

Cited by 128 publications

References 11 publications

Hepatitis C virus and B-cell non-Hodgkin lymphomas: an Italian multicenter case-control study

Hepatitis C virus and B-cell non-Hodgkin lymphomas: an Italian multicenter case-control study

Extrahepatic disorders of HCV infection: A distinct entity of B-cell neoplasia?

Management of Chronic Hepatitis C: Consensus Guidelines

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